109471-39-8

Basic information

• Product Name: 3-methyl-4-(4-methylbenzyl)-1-phenyl-1,4-dihydro-5H-pyrazol-5-one
• Synonyms: 3-methyl-4-(4-methylbenzyl)-1-phenyl-1,4-dihydro-5H-pyrazol-5-one
• CAS NO: 109471-39-8
• Molecular Weight: 278.354
• Mol File: 109471-39-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-methyl-4-(4-methylbenzyl)-1-phenyl-1,4-dihydro-5H-pyrazol-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-4-(4-methylbenzyl)-1-phenyl-1,4-dihydro-5H-pyrazol-5-one(109471-39-8)
• EPA Substance Registry System: 3-methyl-4-(4-methylbenzyl)-1-phenyl-1,4-dihydro-5H-pyrazol-5-one(109471-39-8)

Safety Data

• Hazardous Substances Data: 109471-39-8(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 104-81-4 4-Methylbenzyl bromide 
• 14305-31-8 α-acetyl-4-methylbenzenepropanoic acid ethyl ester 
• 59-88-1 phenylhydrazine hydrochloride 

Downstream Products

• 1374775-37-7 C₂₇H₂₄N₂O₂ 
• 1310584-83-8 C₃₁H₃₂N₂O₄ 
• 1310585-03-5 C₃₁H₃₂N₂O₄ 
• 1310585-21-7 C₃₀H₃₀N₂O₄ 
• 1263574-57-7 (R)-diethyl 1-(3-methyl-4-(4-methylbenzyl)-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)hydrazine-1,2-dicarboxylate 

Relevant articles and documents

Diastereospecific Enantiodivergent Allylation of Pyrazolones as an Entry to β-Aminoamides

A diastereospecific enantiodivergent allylation of pyrazolones is reported which is catalyzed by a planar chiral pentaphenylferrocene based palladacycle. With the same catalyst batch both product enantiomers were selectively available. The method is applicable to structurally diverse substrates and gave products with enantiomeric excesses between 85 and 94%. In addition, we could show that pyrazolones are transformable into β-aminoamides.

Tunable Aerobic Oxidative Hydroxylation/Dehydrogenative Homocoupling of Pyrazol-5-ones under Transition-Metal-Free Conditions

A practical and tunable transition-metal-free aerobic oxidation of pyrazol-5-ones preparing either 4-hydroxypyrazoles (via C-H hydroxylation) or bispyrazoles (via dehydrogenative homocoupling) is described. The K2CO3/dioxane reagent system predominately promoted hydroxylation to deliver the α-hydroxylated pyrazoles. In contrast, the formation of bispyrazoles was overwhelmingly preferred with CH3CN as the reaction medium without any additives.