109504-68-9

Basic information

• Product Name: N-quinoxalin-6-yl-toluene-4-sulfonamide
• CAS NO: 109504-68-9
• Molecular Weight: 299.353
• Mol File: 109504-68-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-quinoxalin-6-yl-toluene-4-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-quinoxalin-6-yl-toluene-4-sulfonamide(109504-68-9)
• EPA Substance Registry System: N-quinoxalin-6-yl-toluene-4-sulfonamide(109504-68-9)

Safety Data

• Hazardous Substances Data: 109504-68-9(Hazardous Substances Data)

Upstream product

• 131543-46-9 Glyoxal 
• 6639-87-8 6-nitroquinoxaline 
• 6298-37-9 6-aminoquinoxaline 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 100881-61-6 N-(5-nitro-quinoxalin-6-yl)-toluene-4-sulfonamide 

Relevant articles and documents

Meta C-H Arylation of Electron-Rich Arenes: Reversing the Conventional Site Selectivity

Controlling site selectivity of C-H activation without using a directing group remains a significant challenge. While Pd(II) catalysts modulated by a mutually repulsive pyridine-type ligand have been shown to favor the relatively electron-rich carbon centers of arenes, reversing the selectivity to favor palladation at the relatively electron-deficient positions has not been possible. Herein we report the first catalytic system that effectively performs meta C-H arylation of a variety of alkoxy aromatics including 2,3-dihydrobenzofuran and chromane with exclusive meta site selectivity, thus reversing the conventional site selectivity governed by native electronic effects. The identification of an effective ligand and modified norbornene (NBE-CO2Me), as well as taking advantage of the statistics, are essential for achieving the exclusive meta selectivity.