1095170-82-3Relevant academic research and scientific papers
5-(1-Acetoxyvinyl)-cyclosaligenyl-2′,3′-dideoxy-2′, 3′- didehydrothymidine monophosphates, a second type of new, enzymatically activated cyclosaligenyl pronucleotides
Gisch, Nicolas,Pertenbreiter, Florian,Balzarini, Jan,Meier, Chris
supporting information; experimental part, p. 8115 - 8123 (2009/12/07)
In our attempt to further develop the cycloSal pronucleotide concept, we report on 5-(1-acetoxyvinyl)-cycloSal-d4TMPs as a new type of enzyme-activated pronucleotides. These compounds were converted into 5-acetyl-cycloSal-d4TMPs by (carboxy)esterase cleav
