1095349-92-0

Basic information

• Product Name: C₁₅H₂₁NO₄S
• Synonyms: C₁₅H₂₁NO₄S
• CAS NO: 1095349-92-0
• Molecular Weight: 311.402
• Mol File: 1095349-92-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₂₁NO₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₂₁NO₄S(1095349-92-0)
• EPA Substance Registry System: C₁₅H₂₁NO₄S(1095349-92-0)

Safety Data

• Hazardous Substances Data: 1095349-92-0(Hazardous Substances Data)

Upstream product

• 2971-79-1 isonipecotic acid methyl ester 
• 609-60-9 2,4-dimethylbenzenesulfonyl chloride 

Downstream Products

• 1418221-47-2 C₁₈H₂₆N₂O₃S 
• 1180561-11-8 C₂₄H₃₀N₂O₃S 
• 1181920-84-2 C₂₀H₂₄N₂O₃S 
• 1286410-63-6 C₁₉H₂₈N₂O₃S 
• 940764-68-1 C₂₁H₂₆N₂O₄S 
• 1053901-96-4 C₂₁H₂₄N₂O₅S 
• 1418221-51-8 C₂₆H₃₄N₄O₄S 
• 1418221-53-0 C₂₁H₂₃F₃N₂O₅S₂ 
• 1418221-55-2 C₂₄H₂₆N₂O₃S 
• 1180106-16-4 C₂₃H₂₅N₃O₃S 
• 757192-81-7 C₁₄H₁₉NO₄S 

Relevant articles and documents

Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors

A series of potent amide non-urea inhibitors of soluble epoxide hydrolase (sEH) is disclosed. The inhibition of soluble epoxide hydrolase leads to elevated levels of epoxyeicosatrienoic acids (EETs), and thus inhibitors of sEH represent one of a novel approach to the development of vasodilatory and anti-inflammatory drugs. Structure-activities studies guided optimization of a lead compound, identified through high-throughput screening, gave rise to sub-nanomolar inhibitors of human sEH with stability in human liver microsomal assay suitable for preclinical development.