109541-23-3Relevant academic research and scientific papers
Diastereoselective synthesis of 3,6-dihydro-2H-1,3,4- thiadiazines
Charrier, Jean-Damien,Reliquet, Alain,Meslin, Jean Claude
, p. 1531 - 1537 (2007/10/03)
Thionation of the benzil hydrazones 3 with Lawesson's reagent afforded the 3,6-dihydxo-2H-1,3,4-thiadiazines 4 by an intramolecular cyclisation. This reaction was shown to be diastereospecific and allowed the formation of the exo compounds 4b-e. When the homochiral SAMP-hydrazone 3f was used, the reaction afforded enantiomerically pure (4R,6R,9S)-4f.
4,5-DIPHENYLIMIDAZOLES FROM THE CYCLIZATION OF BENZIL N-ALKYLMONOHYDRAZONES
Collibee, William L.,Anselme, Jean-Pierre
, p. 655 - 662 (2007/10/02)
The thermal cyclization of monodisubstituted hydrazones (1) affords the corresponding N-substituted-4,5-diphenylimidazoles in good to excellent yields; possible mechanisms for this unusual cyclization are presented.
