1095616-50-4Relevant academic research and scientific papers
A novel approach to γ-hydroxy-α,β-unsaturated compounds
Krawczyk, Henryk,Wasek, Katarzyna,Kedzia, Jacek
experimental part, p. 3299 - 3306 (2009/05/11)
A simple synthesis of (E)-alk-1-enyl mesylates from (E)-alk-1- enylphosphonates is reported. Construction of γ-hydroxy-α,β- unsaturated compounds was achieved by a two-step process involving dihydroxylation of the enol mesylates followed by HWE reaction of the resulting α-hydroxy aldehydes with activated methylphosphonates. Enantioselective synthesis of the title compounds is also reported.
