109562-49-4

Upstream product

• 110-91-8 morpholine 
• 637-69-4 4-Methoxystyrene 
• 50-00-0 formaldehyd 
• 51410-44-7 1-(4-methoxylphenyl)-2-propen-1-ol 
• 5349-60-0 1-(4-methoxyphenyl)-1-propanol 
• 71035-25-1 (E)-1-(4-methoxyphenyl)-3-morpholinoprop-2-en-1-one 

Relevant academic research and scientific papers

A formal anti-Markovnikov hydroamination of allylic alcohols via tandem oxidation/1,4-conjugate addition/1,2-reduction using a Ru catalyst

A formal anti-Markovnikov hydroamination of allylic alcohols using a Ru catalyst via tandem oxidation/1,4-conjugate addition/1,2-reduction was developed. Thus, the reaction of allylic alcohols with amines was performed in the presence of the catalyst generated from RuClH(CO)(PPh3)3 and 2,6-bis(n-butyliminomethyl)pyridine in situ to afford the corresponding γ-amino alcohols efficiently. This journal is

Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols

A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols. Georg Thieme Verlag Stuttgart · New York.