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109581-97-7

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109581-97-7 Usage

General Description

8-Amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione is a chemical compound with a complex molecular structure. It contains a pyranoindolizinoquinoline core with an amino group at the 8th position, an ethyl group at the 4th position, and a hydroxyl group at the 4th position. The compound also features a lactone ring at the 3rd and 14th positions. This chemical may have potential biological activities due to its unique structure and functional groups. Further research and study are required to fully understand the properties and potential applications of this compound.

Check Digit Verification of cas no

The CAS Registry Mumber 109581-97-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,5,8 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 109581-97:
(8*1)+(7*0)+(6*9)+(5*5)+(4*8)+(3*1)+(2*9)+(1*7)=147
147 % 10 = 7
So 109581-97-7 is a valid CAS Registry Number.

109581-97-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 11-amino-20(RS)-camptothecin

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109581-97-7 SDS

109581-97-7Downstream Products

109581-97-7Relevant articles and documents

Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring a substituted camptothecin analogues. Structure-activity correlations

Wani,Nicholas,Manikumar,Wall

, p. 1774 - 1779 (2007/10/02)

Nineteen racemic ring A substituted analogues of the antitumor agent 20(S)-camptothecin were prepared by total synthesis and evaluated for in vitro cytotoxic activity against KB cell culture and in vivo antileukemic activity against L1210. These compounds bore a wide variety of substitutents at C11 designed to confer upon the ring system a broad range of combinations of electronic, steric, and lipophilic effects. A few C10-substituted derivatives as well as C10,C11-disubstituted analogues prepared as part of a concurrent study have also been included for general comparison. With the notable exception of the cyano derivative, the 11-substituted compounds displayed only modest in vitro and in vivo activities, and there was a remarkable insensitivity toward the nature of the substituent. In contrast, the 9- and 10-substituted compounds exhibited a considerably higher level of dose potency and activity both in vitro and in vitro.

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