98276-57-4

Basic information

• Product Name: 2,4-DIAMINOBENZALDEHYDE
• Synonyms: 2,4-DIAMINOBENZALDEHYDE;Benzaldehyde, 2,4-diamino- (6CI, 9CI);Benzaldehyde, 2,4-diaMino-;4-Formylbenzene-1,3-diamine
• CAS NO: 98276-57-4
• Molecular Formula: C₇H₈N₂O
• Molecular Weight: 136.15
• Product Categories: ALDEHYDE;Aromatic Aldehydes & Derivatives (substituted)
• Mol File: 98276-57-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 152℃
• Boiling Point: 364.0±32.0 °C(Predicted)
• Appearance: /
• Density: 1.288±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.86±0.10(Predicted)
• CAS DataBase Reference: 2,4-DIAMINOBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIAMINOBENZALDEHYDE(98276-57-4)
• EPA Substance Registry System: 2,4-DIAMINOBENZALDEHYDE(98276-57-4)

Safety Data

• Hazardous Substances Data: 98276-57-4(Hazardous Substances Data)

Usage

Uses

2,4-Diaminobenzaldehyde is a reagent used in organic synthesis such as in the preparation of 6-?(trifluoromethyl)?-?N-?(4-?oxothiazolidin-?3-?yl)?quinazoline-?2-?carboxamide derivatives as a potential DprE1 inhibitors.

Upstream product

• 102170-39-8 4-amino-2-nitrobenzaldehyde 
• 528-75-6 2,4-dinitrobenzaldehyde 
• 119-32-4 4-Methyl-3-nitroanilin 
• 100796-40-5 4-acetylamino-1-diacetoxymethyl-2-nitro-benzene 
• 109466-84-4 4-nitro-2-aminobenzaldehyde 

Downstream Products

• 109581-97-7 11-amino-20(RS)-camptothecin 
• 67911-35-7 2-Amino-4-(acetylamino)benzaldehyde 
• 339538-56-6 4'-trifluoromethyl-biphenyl-2-carboxylic acid (3-amino-4-formyl-phenyl)-amide 
• 1029773-05-4 7-amino-2-(4-fluorophenyl)quinoline 
• 1224728-33-9 N-(3-amino-4-formylphenyl)-1-hydroxy-2,2,5,5-tetramethyl-3-pyrrolin-1-oxyl-3-carboxamide 

Relevant articles and documents

An improved procedure for the reduction of 2,4-dinitrobenzaldehyde to 2,4-diaminobenzaldehyde with iron and acetic acid under dose-controlled conditions

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Ni@Pd core-shell nanoparticles supported on a metal-organic framework as highly efficient catalysts for nitroarenes reduction

Ni@Pd core-shell nanoparticles with a mean particle size of 8-9 nm were prepared by solvothermal reduction of bivalent nickel and palladium in oleylamine and trioctylphosphine. Subsequently, the first-ever deposition of Ni@Pd core-shell nanoparticles having different compositions on a metal-organic framework (MIL-101) was accomplished by wet impregnation in n-hexane. The Ni@Pd/MIL-101 materials were characterized by powder X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, and energy-dispersive X-ray spectroscopy and also investigated as catalysts for the hydrogenation of nitrobenzene under mild reaction conditions. At 30 °C and 0.1 MPa of H2 pressure, the Ni@Pd/MIL-101 gives a TOF as high as 375 h-1 for the hydrogenation of nitrobenzene and is applicable to a wide range of substituted nitroarenes. The exceptional performance of this catalyst is believed to result from the significant Ni-Pd interaction in the core-shell structure, together with promotion of the conversions of aromatics by uncoordinated Lewis acidic Cr sites on the MIL-101 support.

Methods of making quinoline amides

The present invention relates to methods of making quinoline amides of Formula I below, which are microsomal triglyceride transfer protein inhibitors and can be used as medicines. The present invention also relates to compounds that are used to make quino