109586-46-1Relevant academic research and scientific papers
Method for synthesizing alkyl olefin through coupling of double-bond carbon-hydrogen bond and saturated carbon-hydrogen bond
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Paragraph 0060-0064; 0087, (2021/02/10)
The invention discloses a method for synthesizing alkyl olefin through coupling of a double-bond carbon-hydrogen bond and a saturated carbon-hydrogen bond. According to to the method, one-pot reactionis implemented on olefin and sulfoxide in the presence of ferric salt and hydrogen peroxide to generate alkyl olefin; in the method, sulfoxide is simultaneously used as a hydrocarbylation reagent anda solvent of olefin, and a reaction product is alkyl olefin from sulfoxide alkyl coupled with olefin carbon atoms, so that an olefin carbon chain is increased; the reaction conditions are mild, the selectivity is good, the yield is high, and industrial production is facilitated.
ISOMERIZATION OF ALKENES
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Page/Page column 20-21; 22, (2020/04/25)
The present invention relates to an isomerization method for alkenes, comprising of reaction an alkene with a Ni(I)-compound. By this method, E-Alkenes are obtained in excellent yield.
E-Olefins through intramolecular radical relocation
Kapat, Ajoy,Sperger, Theresa,Guven, Sinem,Schoenebeck, Franziska
, p. 391 - 396 (2019/02/03)
Full control over the selectivity of carbon-carbon double-bond migrations would enable access to stereochemically defined olefins that are central to the pharmaceutical, food, fragrance, materials, and petrochemical arenas. The vast majority of double-bond migrations investigated over the past 60 years capitalize on precious-metal hydrides that are frequently associated with reversible equilibria, hydrogen scrambling, incomplete E/Z stereoselection, and/or high cost. Here, we report a fundamentally different, radical-based approach.We showcase a nonprecious, reductant-free, and atom-economical nickel (Ni)(I)-catalyzed intramolecular 1,3-hydrogen atom relocation to yield E-olefins within 3 hours at room temperature. Remote installations of E-olefins over extended distances are also demonstrated.
Co2(CO)8-mediated Selective Reductions of Propargyl Alcohol Derivatives to Alkenes
Dou, Ying,Xing, Ping,Huang, Zuogang,Jiang, Biao
, p. 999 - 1002 (2016/02/18)
In the presence of Co2(CO)8 and additives, propargyl alcohol derivatives could be reduced to alkenes in moderate to good yield. The selectivity of this reaction could be controlled by adding different additives: with H2O as the additive, the major configuration of product is Z-alkene; with CF3COOH as the additive, the major configuration of product is E-alkene.
A facile and convenient sequential homobimetallic catalytic approach towards β-methylstyrenes. A one-pot Stille cross-coupling/isomerization strategy
Simonetti, Sebastian O.,Larghi, Enrique L.,Kaufman, Teodoro S.
, p. 3735 - 3743 (2014/06/09)
An efficient one-pot synthetic approach towards β-methylstyrenes is reported. The transformation, based on sequential homobimetallic catalysis, involves a Stille cross-coupling reaction between aryl halides and allyltributylstannane, followed by an in situ palladium-catalyzed conjugative isomerization. The reaction was optimized, and the best results were obtained with 10 mol% Pd(PPh3)2Cl2, 8.0 equiv. LiCl, and 0.5 equiv. PPh3 in diglyme at 130 °C for 12 h. It was demonstrated that the reaction tolerates a wide variety of functional groups. This journal is the Partner Organisations 2014.
Heck reaction of aryl bromides with pent-4-en-2-ol, 2-phenylpent-4-en-2-ol, or hept-6-en-3-ol catalysed by a palladium-tetraphosphine complex
Berthiol, Florian,Doucet, Henri,Santelli, Maurice
, p. 3589 - 3602 (2007/10/03)
The tetraphosphine cis,cis,cis-1,2,3,4-tetrakis(diphenylphosphinomethyl) cyclopentane in combination with [Pd(η3-C3H 5)Cl]2 affords a very efficient catalyst for the Heck reaction of aryl bromides with pent-4-en
