1096130-75-4

Usage

Uses

Used in Pharmaceutical and Medicinal Chemistry:
1-(2-methylphenyl)-1H-1,2,3-triazole-4-yl-methanol is used as a building block for heterocyclic compounds in the pharmaceutical and medicinal chemistry industry. Its unique structure allows for the creation of novel drugs with potential therapeutic applications.
Used in Agriculture:
In the agricultural industry, 1-(2-methylphenyl)-1H-1,2,3-triazole-4-yl-methanol is used as a potential active ingredient in the development of new antimicrobial and antifungal agents. Its properties may help in controlling various pathogens that affect crop health and yield.
Used in Materials Science:
Within the materials science field, 1-(2-methylphenyl)-1H-1,2,3-triazole-4-yl-methanol is utilized for its potential to enhance or create new materials with specific properties. Its chemical structure may contribute to the development of advanced materials with applications in various industries.
Overall, 1-(2-methylphenyl)-1H-1,2,3-triazole-4-yl-methanol is a multifaceted compound with a wide range of potential applications across different sectors, including pharmaceuticals, agriculture, and materials science. Its versatility and unique properties make it a valuable asset for researchers and industry professionals alike.

Upstream product

• 31656-92-5 1-azido-2-methyl-benzene 
• 107-19-7 propargyl alcohol 
• 95-53-4 o-toluidine 

Downstream Products

• 1096130-96-9 C₁₁H₁₃N₃O₃S 
• 1325724-91-1 1-(2-methylphenyl)-1H-1,2,3-triazole-4-carbaldehyde 
• 81945-56-4 1-(2-methylphenyl)-1H-1,2,3-triazole 
• 1099631-80-7 1-(o-tolyl)-1H-1,2,3-triazole-4-carboxylic acid 

Relevant academic research and scientific papers

Synthesis, characterization and photodynamic activity against bladder cancer cells of novel triazole-porphyrin derivatives

Novel triazole-porphyrin derivatives (TZ-PORs) were synthesized through the Heck reaction and then incorporated into polyvinylpyrrolidone (PVP) micelles. After verifying that this incorporation did not compromise the photophysical and chemical features of

One-Pot Synthesis of 1-Monosubstituted 1,2,3-Triazoles from Propargyl Alcohol

A one-pot synthesis of 1-monosubstituted-1,2,3-triazoles from propargyl alcohol and various aryl azides was achieved. This simple method provides concise and efficient access to various 1-monosubstituted 1,2,3-triazole derivatives through a three-step one

An efficient NaHSO3-promoted protocol for chemoselective synthesis of 2-substituted benzimidazoles in water

An efficient protocol for chemoselective synthesis of 2-substituted benzimidazoles from a variety of aliphatic/aromatic/ heteroaryl aldehydes and o-phenylenediamine derivatives promoted by NaHSO3 in water had been developed. The amount of NaHSO3 had a great effect on the reaction selectivity of 2-substituted benzimidazole and 1,2-disubstituted benzimidazole when the reaction was carried out in water. When the amount of the NaHSO3 was more than 11 equivalents, the 2-substituted benzimidazole could be highly selectively formed as the sole product. NaHSO3 was firstly reacted with aldehyde to form the aldehyde sodium bisulfite, which reacted with o-phenylenediamine to form the 2-substituted benzimidazole and inhibited the formation of 1,2-disubstituted benzimidazole. This protocol solved the poor selectivity problem appearing in traditional method when cyclocondensation between o-phenylenediamine and aldehydes. The method also had advantage of simple work up by filtrating the single 2-substituted benzimidazole precipitates from reaction mixture at the end of the reaction without further purification. In addition, the method was applicable to both electron-rich and electron-poor starting materials, which was successfully used for synthesizing nine novel 2-substituted benzimidazole derivatives containing a 1,2,3-triazole moiety. They were characterized by NMR, IR and HRMS spectrum. Moreover, this method had been applied to a large scale synthesis of 2-substituted benzimidazole derivatives.

SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS

Substituted 1,2,3-triazoles as NR2B receptor ligands. Such compounds may be used in NR2B receptor modulation and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by NR2B receptor activity.

Design, Synthesis, and Antifungal Evaluation of Novel Benzoxazole Derivatives Containing a 1,2,3-Triazole Moiety

For finding novel bioactive compounds with significant antifungal activities, 17 novel benzoxazole derivatives containing a 1,2,3-triazole moiety were synthesized by the copper(II) acetylacetonate-catalyzed cyclization reaction between 2-aminophenol deriv

Novel 1,2,3-triazole derivatives for use against mycobacterium tuberculosis H37Rv (ATCC 27294) strain

The purpose of this study was to prepare various 4-substituted N-phenyl-1,2,3-triazole derivatives using click chemistry. The derivatives were screened in vitro for antimicrobial activity against Mycobacterium tuberculosis strain H37Rv (ATCC 27294) using

Clubbed [1,2,3] triazoles by fluorine benzimidazole: A novel approach to H37Rv inhibitors as a potential treatment for tuberculosis

A Novel Clubbed [1,2,3] triazoles with fluorine benzimidazole series of H37Rv strain inhibitors, potentially useful for the treatment of tuberculosis is disclosed on the basis of promising results of preliminary antimicrobial study. Evaluation of the SAR