81945-56-4Relevant academic research and scientific papers
A convenient synthesis of 1-substituted 1,2,3-triazoles via CuI/Et 3N catalyzed 'click chemistry' from azides and acetylene gas
Wu, Lu-Yong,Xie, Yong-Xin,Chen, Zi-Sheng,Niu, Yan-Ning,Liang, Yong-Min
, p. 1453 - 1456 (2009)
Copper(I)-catalyzed 'click chemistry' using acetylene gas was successfully explored under mild conditions. 1-Substituted-1,2,3-triazoles were conveniently synthesized from the corresponding aromatic and aliphatic azides. Georg Thieme Verlag Stuttgart.
Microwave-assisted one-pot quick synthesis of 1-monosubstituted 1,2,3-triazoles from arylboronic acids, sodium azide and 3-butyn-2-ols
Du, Zhonglin,Li, Fenrui,Li, Li,Li, Ran
, (2020/11/13)
Abstract: Microwave-assisted one-pot quick synthesis to 1-monosubstituted 1,2,3-triazoles was achieved with good to excellent yields using the widely available arylboronic acids, sodium azide and 3-butyn-2-ols within 15 min. This method features high effi
One-pot synthesis of 1-monosubstituted-1, 2, 3-triazoles from 2-methyl-3-butyn-2-ol
Liu, Yaowen,Han, Chunmei,Ma, Xinyuan,Yang, Jianhua,Feng, Xuepu,Jiang, Yubo
supporting information, p. 650 - 653 (2018/01/15)
An efficient method for the synthesis of 1-monosubstituted-1, 2, 3-triazoles from 2-methyl-3-butyn-2-ol under copper catalyst conditions has been developed through a one-step one-pot sequence. This method provides a concise and efficient pathway to synthesize 1-monosubstituted-1, 2, 3-triazole derivatives in good to excellent yields.
One-Pot Synthesis of 1-Monosubstituted 1,2,3-Triazoles from Propargyl Alcohol
Han, Chunmei,Dong, Suping,Zhang, Wensheng,Chen, Zhen
supporting information, p. 673 - 677 (2018/03/10)
A one-pot synthesis of 1-monosubstituted-1,2,3-triazoles from propargyl alcohol and various aryl azides was achieved. This simple method provides concise and efficient access to various 1-monosubstituted 1,2,3-triazole derivatives through a three-step one
Pd-catalyzed regioselective arylation on the C-5 position of N-aryl 1,2,3-triazoles
Yamajala, K. Durga Bhaskar,Patil, Mahendra,Banerjee, Shaibal
supporting information, p. 3003 - 3011 (2015/03/30)
We herein report a highly efficient method for the arylation at the C-5 position of N-aryl 1,2,3-triazoles via a direct palladium catalyzed arylation reaction. The optimal reaction conditions required a combination of Pd(OAc)2 and tris(o-tolyl)
Green synthesis of 1-monosubstituted 1,2,3-triazoles via 'click chemistry' in water
Wu, Luyong,Yan, Bo,Yang, Guo,Chen, Yuxue
, p. 397 - 400 (2014/01/06)
The copper-catalyzed click reaction of organic azides with acetylene gas to give 1,2,3-triazoles using water as solvent was studied. The best yields are obtained in the presence of 10 mol% of CuI and 20 mol% of Et3N. Several 1-substituted triaz
Facile one-pot synthesis of monosubstituted 1-aryl-1h-1,2,3-triazoles from arylboronic acids and prop-2-ynoic acid (=propiolic acid) or calcium acetylide (=calcium carbide) as acetylene source
Yang, Qing,Jiang, Yubo,Kuang, Chunxiang
experimental part, p. 448 - 454 (2012/05/04)
The synthesis of monosubstituted 1-aryl-1H-1,2,3-triazoles was achieved in a one-pot reaction from arylboronic acids and prop-2-ynoic acid or calcium acetylide (=calcium carbide), respectively, as a source of acetylene, with yields ranging from moderate to excellent (Scheme 1, Table 2). The reaction conditions were successfully applied to arylboronic acids, including analogs with various functionalities. Unexpectedly, the 1,2,3-triazole moiety promoted a regioselective hydrodebromination (Scheme 2). Copyright
Facile and quick synthesis of 1-monosubstituted aryl 1,2,3-triazoles: A copper-free [3+2] cycloaddition
Jiang, Yubo,Kuang, Chunxiang,Yang, Qing
experimental part, p. 289 - 292 (2011/02/28)
An efficient copper-free synthesis of 1-monosubstituted aryl 1,2,3-triazoles from sodium acetylide and aryl azides was developed, which was found suitable for various aryl azides and completed within 15 min at room temperature with moderate to excellent y
A novel approach to 1-monosubstituted 1,2,3-triazoles by a click cycloaddition/decarboxylation process
Xu, Mei,Kuang, Chunxiang,Wang, Zhuo,Yang, Qing,Jiang, Yubo
supporting information; experimental part, p. 223 - 228 (2011/03/18)
The synthesis of 1-monosubstituted 1,2,3-triazoles was achieved using azides and propiolic acid by copper-catalyzed click cycloaddition/ decarboxylation, which was easily carried out in N,N-dimethylformamide at room temperature or 60 C with yields ranging
The use of calcium carbide in the synthesis of 1-monosubstituted aryl 1,2,3-triazole via click chemistry
Jiang, Yubo,Kuang, Chunxiang,Yang, Qing
experimental part, p. 3163 - 3166 (2010/03/04)
The synthesis of 1-monosubstituted aryl 1,2,3-triazoles was achieved using calcium, carbide as a source of acetylene. The copper-catalyzed 1,3-dipolar cycloaddition reactions were carried out without nitrogen protection and in a MeCN - H2O mixt
