1096296-85-3

Basic information

• Product Name: 5-Bromo-2-chlorobenzyl amine
• Synonyms: 5-Bromo-2-chlorobenzyl amine;BenzeneMethanaMine, 5-broMo-2-chloro-;(5-BroMo-2-chlorophenyl)MethanaMine;(5-Bromo-2-chlorophenyl)
• CAS NO: 1096296-85-3
• Molecular Formula: C₇H₇BrClN
• Molecular Weight: 220.49418
• Mol File: 1096296-85-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 277.841 °C at 760 mmHg
• Flash Point: 121.834 °C
• Appearance: /
• Density: 1.603 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-Bromo-2-chlorobenzyl amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-chlorobenzyl amine(1096296-85-3)
• EPA Substance Registry System: 5-Bromo-2-chlorobenzyl amine(1096296-85-3)

Safety Data

• Hazardous Substances Data: 1096296-85-3(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-chlorobenzyl amine is a chemical compound with the molecular formula C7H7BrClN. It is a primary and secondary amine compound with a benzyl group substituted with a bromine atom at the 5th position and a chlorine atom at the 2nd position. 5-Bromo-2-chlorobenzyl amine is commonly used in organic synthesis and pharmaceutical research as a reagent and intermediate. It can be used in the preparation of various organic compounds, including pharmaceuticals, agrochemicals, and materials. Its properties and structure make it a valuable building block in the synthesis of complex molecules. Additionally, it has potential application in the development of new therapeutic agents and other bioactive compounds. Overall, 5-Bromo-2-chlorobenzyl amine is an important chemical for research and development in the pharmaceutical and organic chemistry industries.

Upstream product

• 21739-92-4 5-bromo-2-chlorobenzoic acid 
• 21900-52-7 5-bromo-2-chloro-benzoyl chloride 
• 188774-55-2 5-bromo-2-chlorobenzamide 
• 251085-86-6 methyl N-[(5-bromo-2-chlorophenyl)methyl]carbamate 
• 57381-44-9 5-bromo-2-chlorobenzonitrile 
• 478374-91-3 2-(azidomethyl)-4-bromo-1-chlorobenzene 

Downstream Products

• 1152088-54-4 4-(5-bromo-2-chlorobenzylamino)-2-chloro-5-nitropyrimidine 
• 1241946-96-2 C₁₄H₁₀BrClFNO 
• 1300611-12-4 N-[(5-bromo-2-chlorophenyl)methyl]acetamide 
• 1338254-30-0 N-(5-bromo-2-chloro-benzyl)-2,2-diethoxy-acetamidine 
• 478374-92-4 tert-butyl 5-bromo-2-chlorobenzylcarbamate 

Relevant articles and documents

STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI

The present invention relates to novel strobilurine type compounds I, processes for preparing these compounds, a use of compounds of the formula I and/or their agriculturally useful salts for controlling phytopathogenic fungi, to compositions comprising at least one such compound, to plant health applications, and to seeds coated with at least one such compound.

Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors

A pyridazin-4-one fragment 4 (hCatS IC50 = 170 μM) discovered through Tethering was modeled into cathepsin S and predicted to overlap in S2 with the tetrahydropyridinepyrazole core of a previously disclosed series of CatS inhibitors. This fragment served as a template to design pyridazin-3-one 12 (hCatS IC50 = 430 nM), which also incorporates P3 and P5 binding elements. A crystal structure of 12 bound to Cys25Ser CatS led to the synthesis of the potent diazinone isomers 22 (hCatS IC50 = 60 nM) and 27 (hCatS IC50 = 40 nM).