109632-38-4Relevant academic research and scientific papers
Rhodium-Catalyzed Direct C-H Phosphorylation of (Hetero)arenes Suitable for Late-Stage Functionalization
Min, Minsik,Kang, Dahye,Jung, Sungwoo,Hong, Sungwoo
, p. 1296 - 1301 (2016)
Efficient rhodium-catalyzed direct C-H phosphorylation of (hetero)arenes was developed. Various directing groups and a wide range of substrates, including heterocycles, can be utilized in this C-H phosphorylation process, allowing for the rapid installation of the phosphonate group into medicinally and biologically important privileged scaffolds. The efficient and straightforward method could serve as a new tool to streamline late-stage C-H functionalization for preparing aryl phosphonates, which are important structural motif in synthetic and medicinal chemistry.
AN UNEXPECTED REACTIVITY OF SIMPLE HETEROGENEOUS MIXTURE OF γ-ALUMINA AND POTASSIUM FLUORIDE : 1-HYDROXYALKANE PHOSPHONIC ESTERS SYNTHESIS FROM NON-ACTIVATED KETONES IN "DRY MEDIA".
Texier-Boullet, Francoise,Lequitte, Maryvonne
, p. 3515 - 3516 (2007/10/02)
1-Hydroxyalkane phosphonic esters are readily obtained from non-activated ketones and dialkylphosphites by absorbing them together on a heterogeneous γ-alumina-potassium fluoride mixture.
