109658-32-4

Basic information

• Product Name: 4-(4-pyridyl)-6-methyl-3-cyano-2(1H)-pyridinethione
• Synonyms: 4-(4-pyridyl)-6-methyl-3-cyano-2(1H)-pyridinethione
• CAS NO: 109658-32-4
• Molecular Weight: 227.29
• Mol File: 109658-32-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-pyridyl)-6-methyl-3-cyano-2(1H)-pyridinethione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-pyridyl)-6-methyl-3-cyano-2(1H)-pyridinethione(109658-32-4)
• EPA Substance Registry System: 4-(4-pyridyl)-6-methyl-3-cyano-2(1H)-pyridinethione(109658-32-4)

Safety Data

• Hazardous Substances Data: 109658-32-4(Hazardous Substances Data)

Upstream product

• 75055-73-1 1-(4-pyridyl)-1,3-butanedione 
• 7357-70-2 Cyanothioacetamide 
• 872-85-5 pyridine-4-carbaldehyde 
• 67-64-1 acetone 

Downstream Products

• 120195-34-8 2-Benzylthio-6-methyl-4-(4-pyridyl)pyridin-3-carbonitrile 

Relevant articles and documents

Synthesis of 3-cyano-6-methyl-4-pyridyl and 3-cyano-4-methyl-6-pyridyl-pyrid-2(1H)-ones

The reaction of the asymmetric substituted 1,3-diketones 1 and 2 with cyanoacetamide (5) and cyanothioacetamide (6), respectively, gave the 4-pyridyl substituted A/8, C/11 and C/12, respectively, as main products; besides the 6-pyridyl substituted pyridone B/9 was formed as main product.As by-products the 6-pyridyl substituted B/10, D/13 and D/14 were found as well as the 4-pyridyl substituted A/7.The separation of the pyridones and thiopyridones succeeded by fractionated crystallization.The reaction of the thiopyridones C/11 and C/12 with ethyl chloroacetate gave the corresponding thienopyridines 15 and 16, respectively.The confirmation of the structures of the isomeric pyridones A/7, B/9 and A/8, B/10, respectively, as well as the thiopyridones C/11, D/13 and C/12, D/14, respectively, was provided by analytical methods, as 13C-NMR-, mass- and UV-VIS-spectra.