1096663-75-0Relevant academic research and scientific papers
Olefin metathesis based approach to diversely functionalized pyrrolizidines and indolizidines; total synthesis of (+)-monomorine
Lesma, Giordano,Colombo, Alessia,Sacchetti, Alessandro,Silvani, Alessandra
experimental part, p. 590 - 596 (2009/06/20)
New scaffolds for the stereoselective synthesis of diversely functionalized chiral enantiopure indolizidines and pyrrolidines were synthesized from the cross and ring-closing metathesis reactions of appropriate intermediates, readily available from L-pyroglutamic acid. The versatility of this strategy was demonstrated by the synthesis of an indolizidine-based azasugar analogue and of the natural alkaloid (+)-monomorine.
