109717-73-9

Usage

Uses

Used in Pharmaceutical Industry:
(S)-3,4-dimethoxyphenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl-methanol is used as a potential pharmaceutical agent for its ability to interact with biological targets. Its complex structure, including the phenyl ring and methoxy groups, may allow it to modulate the function of these targets, making it a candidate for the development of new drugs.
Used in Chemical Research:
In the field of chemical research, (S)-3,4-dimethoxyphenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl-methanol serves as a subject of study for understanding its properties, reactivity, and potential applications in various chemical processes. Its chiral nature and complex structure make it an interesting compound for researchers to explore.
Used in Drug Design and Development:
(S)-3,4-dimethoxyphenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl-methanol is used as a lead compound in drug design and development. Its specific spatial arrangement of atoms, indicated by the (S) configuration, could be crucial for its interaction with biological targets, making it a valuable starting point for the creation of new therapeutic agents.

Upstream product

• 20345-69-1 3,4-dihydropapaveraldine 
• 106647-99-8 (+/-)-erythro-N-(ethoxycarbonyl)hydroxynorlaudanosine 
• 106647-99-8 (+/-)-threo-N-(ethoxycarbonyl)hydroxynorlaudanosine 
• 109717-72-8 (-)-threo-N-(ethoxycarbonyl)hydroxynorlaudanosine 
• 80245-51-8 4-lithio-1,2-dimethoxybenzene 
• 182892-23-5 (S)-2-Acetyl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline-1-carbaldehyde 
• 2859-78-1 4-Bromoveratrole 
• 173266-44-9 (S)-1-((1S,5R,7R)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid methyl ester 
• 486-99-7 (S)-1-hydroxymethyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 486-99-7 (6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinolyl)methanol 
• 109663-58-3 (S)-2-(ethoxycarbonyl)calycotomine 
• 109663-60-7 (S)-2-ethoxycarbonyl-1-formyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 182892-22-4 1-[(S)-6,7-Dimethoxy-1-((1R,2R,3R,4S)-1,2,3,4,5-pentahydroxy-pentyl)-3,4-dihydro-1H-isoquinolin-2-yl]-ethanone 
• 257633-01-5 (6,7-Dihydroxy-1,2,3,4-tetrahydro-isoquinolin-1-yl)-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-methanone 

Downstream Products

• 109717-70-6 1c-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-(10br)-1,5,6,10b-tetrahydro-oxazolo[4,3-a]isoquinoline 
• 62926-32-3 (+/-)-threo-(O,N-diacetyl)hydroxynorlaudanosine 
• 50896-90-7 (-) N-norlaudanosine 
• 6872-27-1 (R)-(+)-xylopinine 
• 85-63-2 (R)-laudanosine 

Relevant academic research and scientific papers

Pictet-Spengler reaction of biogenic amines with (2R)-N- glyoxyloylbornane-10,2-sultam. Enantioselective synthesis of (S)-(+)-N- methylcalycotomine and (R)-(+)-xylopinine

The Pictet-Spengler reaction of (2R)-N-glyoxyloylbornane-10,2-sultam with dopamine hydrochloride gave the condensation product, which was further converted into (S)-(+)-N)-methylcalycotomine and (R)-(+)-xylopinine of high enantiomeric purity.

Enantioselective synthesis of (R)-(-)-laudanosine and (R)-(-)-glaucine from L-ascorbic acid

L-Ascorbic acid 1 was converted into L-gulonolactone 2 by catalytic hydrogenation. Treatment of 2 with 3,4-dimethoxyphenylethyl amine 3 afforded amide 4, which in several steps was transformed into the title alkaloids in good enantiomeric excesses. Also, chromium(III) oxide is proposed as an effective catalyst for the conversion of (R)-(-)-laudanosine into (R)-(-)-glaucine.

BENZOPHENANTHRIDINES. VI. TRANSFORMATIONS OF PROTOBERBERINE ALKALOIDS INTO BENZOPHENANTHRIDINE ALKALOIDS. HOFMANN DEGRADATION OF α-N- AND β-N-METHYL-(+/-)-13α-HYDROXYXYLOPININE IODIDES

(+/-)-13α-Hydroxyxylopinine was synthesized from 3,4-dihydropapaverine dichlorophosphate through a stage involving the formation of 3,4-dihydropapaveraldine and α-hydroxynorlaudanosine.The product was converted by the action of methyl iodide in ethanol in