1097223-32-9Relevant academic research and scientific papers
Synthesis of Dihydrophenanthridines and Oxoimidazolidines from Anilines and Ethylglyoxylate via Aza Diels-Alder Reaction of Arynes and KF-Induced Annulation
Reddy, R. Santhosh,Lagishetti, Chandraiah,Chen, Shuo,Kiran, I. N. Chaithanya,He, Yun
, p. 4546 - 4549 (2016/09/28)
The transition-metal-free multicomponent coupling of arynes, anilines, and ethylglyoxylate, proceeding via an inverse electron-demand aza Diels-Alder cycloaddition and N-arylation, has been demonstrated. This protocol allows rapid access to N-aryl dihydrophenanthridine derivatives in moderate to high yields at room temperature from readily available starting materials. In addition, an unprecedented fluoride induced annulation of ethyl(arylimino)acetates led to the formation of highly functionalized oxoimidazolidine derivatives in good yields under mild conditions.
Phosphine-catalyzed annulation of ethyl (arylimino)acetates: Synthesis of highly functionalized oxoimidazolidines
Ma, Guang-Ning,Wang, Fei-Jun,Gao, Jun,Shi, Min
supporting information; scheme or table, p. 4998 - 5000 (2009/06/05)
This paper describes an unexpected and novel nucleophilic phosphine-catalyzed annulation of ethyl (arylimino)acetates to give polysubstituted oxoimidazolidine derivatives in moderate to good yields from simple and easily available starting materials under
