1097870-77-3

Upstream product

• 893738-65-3 2-(4-cyclopropylphenyl)acetonitrile 
• 16532-79-9 4-Bromophenylacetonitrile 
• 40641-90-5 2-(4-cyclopropylphenyl)acetic acid 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 

Relevant academic research and scientific papers

COMBINATIONS OF AKT INHIBITOR COMPOUNDS AND VEMURAFENIB, AND METHODS OF USE

The invention provides a combination of a) a compound of Formula Ia: [insert Formula Ia], or a pharmaceutically acceptable salt thereof, and b) vemurafenib or a pharmaceutically acceptable salt thereof for the prophylactic or therapeutic treatment of a hy

PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS

The present invention provides compounds of Formula (I), including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.