1097871-99-2

Usage

Uses

Used in Pharmaceutical Industry:
(4-cyano-3-fluorophenyl)acetic acid is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications, making it a valuable component in medicinal chemistry.
Used in Organic Synthesis:
In the realm of organic chemistry, (4-cyano-3-fluorophenyl)acetic acid serves as a building block for the creation of complex organic molecules. Its presence in the synthesis process can lead to the formation of novel materials with a range of properties and potential uses.
Used in Research and Development:
(4-cyano-3-fluorophenyl)acetic acid is also employed in research and development settings, where it is studied for its pharmacological properties and potential applications in the creation of new materials. This makes it an important tool for scientists and researchers working at the forefront of organic chemistry and drug discovery.

Upstream product

• 1402585-15-2 C₁₃H₁₄FNO₂ 
• 1402585-14-1 C₁₂H₁₄FIO₂ 
• 1402585-13-0 C₁₂H₁₆FNO₂ 
• 1402585-12-9 C₁₂H₁₄FNO₄ 
• 1493-27-2 ortho-nitrofluorobenzene 
• 124-38-9 carbon dioxide 
• 85070-67-3 2-fluoro-4-methylbenzonitrile 

Downstream Products

• 1255207-55-6 2-fluoro-4-oxiran-2-ylbenzonitrile 
• 1255207-56-7 2-(4-cyano-3-fluorophenyl)ethyl methanesulfonate 
• 433939-83-4 4-ethenyl-2-fluorobenzonitrile 
• 1402581-28-5 N-[[2-(3-chlorophenyl)-5-(trifluoromethyl)-2H-pyrazol-3-yl]methyl]-2-[3-fluoro-4-(hydroxymethyl)phenyl]acetamide 
• 1402585-17-4 C₂₁H₁₆ClF₄N₃O₃ 
• 1402586-71-3 C₂₀H₁₄ClF₄N₃O₃ 
• 1402585-16-3 C₂₀H₁₃ClF₄N₄O 
• 942282-42-0 2-fluoro-4-(2-hydroxyethyl)benzonitrile 

Relevant academic research and scientific papers

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula(I) or a pharmaceutically acceptable salt thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure, kidney disease, edema, and conditions associated with excessive salt and water retention.

SUBSTITUTED PYRAZOLYL-BASED CARBOXAMIDE AND UREA DERIVATIVES BEARING A PHENYL MOIETY SUBSTITUTED WITH AN O-CONTAINING GROUP AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted pyrazolyl-based carboxamide and urea derivatives of formula (Q) as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

This invention relates to compounds having structural Formula I: and pharmaceutically acceptable salts thereof which are inhibitors of the Renal Outer Medullary Potassium (ROMK) channel (Kir1.1). The compounds of Formula I are useful as diuretics and natriuretics and therefore are useful for the therapy and prophylaxis of disorders resulting from excessive salt and water retention, including cardiovascular diseases such as hypertension and chronic and acute heart failure