109876-48-4Relevant academic research and scientific papers
Sulfurization of Azines; Part IX. (1-Chloroalkylthio)-azines
Maslankiewicz, Andrzej,Skrzypek, Leszek
, p. 835 - 839 (1986)
Chlorination of 2-, 3-, or 4-alkylthioquinolines (or -pyridines) with N-chlorosuccinimide or sulfuryl chloride affords 2-, 3-, or 4-(1-chloroalkylthio)-quinolines (or -pyridines), respetively, which in the case of ethyl or propyl compounds can be dehydrochlorinated to 1-alkenylthio derivatives. 4-Chloro-3-(1-chloroalkylthio)-quinolines react with thiourea to give 2-alkyl-1,3-dithioloquinolines.
SPECIFIC C-H...N INTRAMOLECULAR INTERACTIONS IN THE VINYLOXY- AND VINYLTHIOPYRIDINE SERIES
Afonin, A. V.,Andriyankov, M. A.,Nikitin, M. V.,Garashchenko, Z. M.,Khil'ko, M. Ya
, p. 863 - 866 (2007/10/02)
A weak hydrogen bond with the participation of the vinyl group α-hydrogen atom arises in 2-vinyloxypyridine and 2-vinylthiopyridine, which primarily exist in the s-trans-conformation, according to the 1H and 13C NMR data.This interaction does not take place in 2-vinyloxymethyl- and 2-vinyloxyethylpyridines, which primarily exist in the s-cis-conformation.The C-H...N intramolecular interaction also does not occur in o-vinyloxyaniline due to the specific features of the stereoelectronic state of the amino group nitrogen atom.
