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Succinimidyl-6-(bromoacetamido)caproate, also known as Sulfo-SBED, is a crosslinking reagent widely utilized in the fields of chemical biology and proteomics research. It is characterized by the presence of a succinimide ester group that readily reacts with primary amines on proteins, leading to the formation of stable amide bonds. Additionally, it features a biotin group that facilitates the purification and detection of the labeled proteins. The bromoacetamido group incorporated within Sulfo-SBED enables the introduction of a bromine atom into the crosslinked proteins, which can be employed for further chemical manipulations or analysis. This reagent serves as a versatile tool for elucidating the functional connections between proteins and for the identification of potential drug targets.

109880-16-2

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109880-16-2 Usage

Uses

Used in Chemical Biology and Proteomics Research:
Succinimidyl-6-(bromoacetamido)caproate is used as a crosslinking reagent for studying protein-protein interactions. Its succinimide ester group allows for the covalent attachment of proteins, while the biotin group enables their purification and detection. This application is crucial for understanding the complex networks of protein interactions within biological systems.
Used in Drug Target Identification:
Sulfo-SBED is employed as a tool for identifying potential drug targets. The ability to crosslink and label proteins with this reagent aids researchers in pinpointing proteins that may be involved in disease pathways or other biological processes, thereby contributing to the discovery of novel therapeutic agents.
Used in Further Chemical Manipulations or Analysis:
The bromoacetamido group in Succinimidyl-6-(bromoacetamido)caproate allows for the introduction of a bromine atom into crosslinked proteins. This feature is used for further chemical manipulations or analysis, providing researchers with additional handles to probe protein structure, function, or interactions in greater detail.

Check Digit Verification of cas no

The CAS Registry Mumber 109880-16-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,8,8 and 0 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 109880-16:
(8*1)+(7*0)+(6*9)+(5*8)+(4*8)+(3*0)+(2*1)+(1*6)=142
142 % 10 = 2
So 109880-16-2 is a valid CAS Registry Number.

109880-16-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (2,5-dioxopyrrolidin-1-yl) 6-[(2-bromoacetyl)amino]hexanoate

1.2 Other means of identification

Product number -
Other names Succinimidyl-6-(bromoacetamido)caproate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109880-16-2 SDS

109880-16-2Downstream Products

109880-16-2Relevant academic research and scientific papers

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