109888-48-4Relevant academic research and scientific papers
Beyond azide-alkyne click reaction: Easy access to 18F-labelled compounds via nitrile oxide cycloadditions
Zlatopolskiy, Boris D.,Kandler, Rene,Kobus, Diana,Mottaghy, Felix M.,Neumaier, Bernd
supporting information; experimental part, p. 7134 - 7136 (2012/07/27)
Radiofluorinated 4-fluorobenzonitrile oxide and N-hydroxy-4- fluorobenzimidoyl chloride rapidly react with different alkenes and alkynes under mild conditions. These cycloadditions are suitable for the preparation of low-molecular weight radiopharmaceutic
Cyclohexylamine derivatives as subtype selective N-methyl-D-aspartate antagonists
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Page 51, (2010/11/30)
Described are cyclohexylamine derivatives of Formula I Formula VI andFormula VIa and pharmaceutically acceptable salts thereof, wherein R1, g, *, R, V, B, E, Y, G, H, X1, and d are as defined in the description. The compounds of Formulas I and VI are antagonists of NMDA receptor channel complexes useful for treating cerebral vascular disorders such as, for example, stroke, cerebral ischemia, trauma, hypoglycemia, anxiety, migraine headache, convulsions, Parkinson's disease, aminoglycoside antibiotics-induced hearing loss, psychosis, glaucoma, CMV retinitis, opioid tolerance or withdrawal, chronic pain, or urinary incontinence.
