109890-22-4Relevant academic research and scientific papers
Cardiotonic agents. 7. Inhibition of separated forms of cyclic nucleotide phosphodiesterase from guinea pig cardiac muscle by 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds. Structure-activity relationships and correl
Sircar,Weishaar,Kobylarz,Moos,Bristol
, p. 1955 - 1962 (2007/10/02)
The structure-activity relationships of a series of 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds were investigated for the in vivo inhibition of different forms of cyclic nucleotide phosphodiesterase (PDE) isolated
6-(Substituted phenyl)-4,5-dihydro-3(2H)-pyridazinone compounds
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, (2008/06/13)
6-(Substituted phenyl)-4,5-dihydro-3(2H)-pyridazinone compounds possessing strong platelet aggregation inhibiting activity and blood pressure depressing activity, having the general formula: STR1 wherein R1 is hydrogen or lower alkyl; R2/
