109904-35-0

Basic information

• Product Name: N,N-dimethyl alpha-(2-oxo 2,4,5,6,7,7a-hexahydro thieno [3,2-c] 5-pyridyl) (2-chloro phenyl)-acetamide
• Synonyms: N,N-dimethyl alpha-(2-oxo 2,4,5,6,7,7a-hexahydro thieno [3,2-c] 5-pyridyl) (2-chloro phenyl)-acetamide
• CAS NO: 109904-35-0
• Molecular Weight: 350.869
• Mol File: 109904-35-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl alpha-(2-oxo 2,4,5,6,7,7a-hexahydro thieno [3,2-c] 5-pyridyl) (2-chloro phenyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl alpha-(2-oxo 2,4,5,6,7,7a-hexahydro thieno [3,2-c] 5-pyridyl) (2-chloro phenyl)-acetamide(109904-35-0)
• EPA Substance Registry System: N,N-dimethyl alpha-(2-oxo 2,4,5,6,7,7a-hexahydro thieno [3,2-c] 5-pyridyl) (2-chloro phenyl)-acetamide(109904-35-0)

Safety Data

• Hazardous Substances Data: 109904-35-0(Hazardous Substances Data)

Upstream product

• 109904-37-2 5,6,7,7a-tetrahydrothieno[3,2-c]pyridine-2(4H)-one monohydrochloride 
• 10421-85-9 2-chloromandelic acid 

Relevant articles and documents

Thiopheneglyoxylic pyridine derivative and its preparation method and medical use

The invention belongs to the field of pharmaceutical chemistry technology, and particularly discloses thienopyridine derivatives, and preparation methods and a medical use thereof. Through structural modification of clopidogrel and prasugrel, a series of new thienopyridine derivative compounds are synthesized and mainly include derivatives esterified with ligustrazine formic acid and shikimic acid; the compounds go into a body, then are rapidly metabolized into effective metabolites and ligustrazine formic acid or shikimic acid, successfully keep away from metabolism of CYP2C19 enzyme, can be directly metabolized into active compounds to play a pharmacological function, thereby solving the clopidogrel resistance problem, effectively improving the compound antithrombotic activity, and also having no significant effect on hemorrhage risk; and the compounds have relatively ideal protective function on liver and kidney, and also have potential therapeutic significance for other cardiovascular diseases.