109923-60-6

Basic information

• Product Name: N⁶0-(4,4'-dimethoxytrityl)-3'-O-tosyladenosine
• Synonyms: N⁶0-(4,4'-dimethoxytrityl)-3'-O-tosyladenosine
• CAS NO: 109923-60-6
• Molecular Weight: 723.806
• Mol File: 109923-60-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N⁶0-(4,4'-dimethoxytrityl)-3'-O-tosyladenosine(CAS DataBase Reference)
• NIST Chemistry Reference: N⁶0-(4,4'-dimethoxytrityl)-3'-O-tosyladenosine(109923-60-6)
• EPA Substance Registry System: N⁶0-(4,4'-dimethoxytrityl)-3'-O-tosyladenosine(109923-60-6)

Safety Data

• Hazardous Substances Data: 109923-60-6(Hazardous Substances Data)

Upstream product

• 58-61-7 adenosine 
• 118364-69-5 2',5'-bis-O-(t-butyldimethylsilyl)-N⁶-(4,4'-dimethoxytrityl)adenosine 
• 98-59-9 p-toluenesulfonyl chloride 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 65109-11-7 2',5'-bis-O-(tert-butyldimethylsilyl)adenosine 
• 109923-59-3 N⁶,O^5'-bis-(4,4'-dimethoxytrityl)-3'-O-tosyladenosine 

Relevant articles and documents

The Synthesis of C-Methyl Branched-Chain Deoxy Sugar Nucleosides by the Deoxygenative Methylation of O-Tosylated Adenosines with Grignard Reagents

The reaction of appropiately protected 2'-O-tosyladenosines with methylmagnesium bromide (or iodide) gave 9-(2-deoxy-3-C-methyl-β-D-threopentofuranosyl)adenine after deprotection.The same reaction on 3'-O-tosyladenosine derivatives afforded an epimeric pair of 2'-C-methyl-3'-deoxy sugar nucleosides.The modified structures of the sugar moieties were determined unambiguously.