109986-03-0Relevant articles and documents
Epoxidation of Olefinic Compounds with Combined Use of Molecular Oxygen and Propionaldehyde Diethyl Acetal Catalyzed by Cobalt(II) Complex. Efficient Method for the Preparation of Acid-sensitive Epoxides
Yorozu, Kiyotaka,Takai, Toshihiro,Yamada, Tohru,Mukaiyama, Teruaki
, p. 1579 - 1582 (1993)
Synthesis of acid-sensitive epoxides such as epoxide of bishomoallyl alcohol or chromene oxide was achieved by the epoxidation of corresponding olefins with combined use of molecular oxygen and propionaldehyde diethyl acetal catalyzed by cobalt(II) comple
Total synthesis of (+)-blennolide C and (+)-gonytolide C via spirochromanone
Adachi, Kanna,Hasegawa, Sho,Katakawa, Kazuaki,Kumamoto, Takuya
, p. 4479 - 4482 (2017/10/30)
We report the asymmetric total synthesis of (+)-blennolide C and (+)-gonytolide C isolated from endophytic fungi. The synthesis involved construction of a spirochromanone with a chiral quaternary carbon by the aldol reaction of o-hydroxyacetophenones and
Stereoselective synthesis of optically active cyclitol precursors via a chemoenzymatic method
Oguzkaya, Funda,Sahin, Ertan,Tanyeli, Cihangir
, p. 3004 - 3009 (2007/10/03)
Racemic α′-acetoxy α,β-unsaturated cyclohexanone has been converted to the corresponding enantiomerically enriched α′-hydroxylated and acetoxylated compounds with 97% ee via enzymatic resolution with PLE. OsO4-Catalyzed dihydroxylation of enant
A Novel Method for the Preparation of Acid-Sensitive Epoxides from Olefins with the Combined Use of Molecular Oxygen and Aldoacetal Catalyzed by a Cobalt(II) Complex
Yorozu, Kiyotaka,Takai, Toshihiro,Yamada, Tohru,Mukaiyama, Teruaki
, p. 2195 - 2202 (2007/10/02)
An efficient synthesis of acid-sensitive epoxides, such as chromene oxide or epoxide of γ,δ-unsaturated alcohol, was successfully achieved by the oxygenation of corresponding olefins with the combined use of an atmospheric pressure of molecular oxygen and aldoacetal catalyzed by a cobalt(II) complex coordinated with the 1,3-diketone ligand.The reactions proceeded under mild and neutral conditions, and the desired epoxides were obtained in good yields.Neither overoxidation nor decomposition of the formed epoxide was observed under the present reaction conditions.Furthermore, various silyl enol ethers and silyl ketene acetals, acid-sensitive compounds, were also smoothly monooxygenated into the corresponding α-hydroxy ketones and α-hydroxy carboxylic acid esters, respectively.
