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1100575-44-7

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1100575-44-7 Usage

General Description

The chemical compound (R)-1-(2-Chloro-6-fluorophenyl)ethanaMine hydrochloride is a derivative of phenylethylamine with a molecular formula C8H10ClF2N·HCl. It is a chiral compound, with a specific orientation around the carbon atom, and is typically used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. (R)-1-(2-Chloro-6-fluorophenyl)ethanaMine hydrochloride is known for its potential as a building block in the creation of various biologically active molecules. Its hydrochloride salt form allows for improved solubility and stability, making it more suitable for use in pharmaceutical formulations. Additionally, it may have applications in research and development, particularly in the study of the structure-activity relationships of biologically active compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 1100575-44-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,0,5,7 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1100575-44:
(9*1)+(8*1)+(7*0)+(6*0)+(5*5)+(4*7)+(3*5)+(2*4)+(1*4)=97
97 % 10 = 7
So 1100575-44-7 is a valid CAS Registry Number.

1100575-44-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R)-1-(2-chloro-6-fluorophenyl)ethanamine,hydrochloride

1.2 Other means of identification

Product number -
Other names (R)-1-(2-CHLORO-6-FLUOROPHENYL)ETHANAMINE-HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1100575-44-7 SDS

1100575-44-7Downstream Products

1100575-44-7Relevant articles and documents

Native Amine-Directed ortho -C-H Halogenation and Acetoxylation /Condensation of Benzylamines

Chand-Thakuri, Pratibha,Alahakoon, Indunil,Liu, Daniel,Kapoor, Mohit,Kennedy, John F.,Jenkins, Kenneth W.,Rabon, Allison M.,Young, Michael C.

, p. 341 - 354 (2021/10/07)

Free or unfunctionalized benzylamines are well known to participate in C-H activation in the presence of palladium salts. Despite the ease with which these complexes can be activated, subsequent functionalization of the dimeric cyclometalates can be chall

Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors

Teng, Xin,Keys, Heather,Jeevanandam, Arumugasamy,Porco Jr., John A.,Degterev, Alexei,Yuan, Junying,Cuny, Gregory D.

, p. 6836 - 6840 (2008/03/14)

Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling non-regulated necrosis. This form of cell death can be induced in an array of cell types in apoptotic deficient conditions with death receptor family ligands. A series of [1,2,3]thiadiazole benzylamides was found to be potent necroptosis inhibitors (called necrostatins). A structure-activity relationship study revealed that small cyclic alkyl groups (i.e. cyclopropyl) and 2,6-dihalobenzylamides at the 4- and 5-positions of the [1,2,3]thiadiazole, respectively, were optimal. In addition, when a small alkyl group (i.e. methyl) was present on the benzylic position all the necroptosis inhibitory activity resided with the (S)-enantiomer. Finally, replacement of the [1,2,3]thiadiazole with a variety of thiophene derivatives was tolerated, although some erosion of potency was observed.

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