87327-70-6

Basic information

• Product Name: 1-(2-chloro-6-fluorophenyl)ethan-1-ol
• Synonyms: 1-(2-chloro-6-fluorophenyl)ethan-1-ol
• CAS NO: 87327-70-6
• Molecular Weight: 174.602
• Mol File: 87327-70-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-(2-chloro-6-fluorophenyl)ethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloro-6-fluorophenyl)ethan-1-ol(87327-70-6)
• EPA Substance Registry System: 1-(2-chloro-6-fluorophenyl)ethan-1-ol(87327-70-6)

Safety Data

• Hazardous Substances Data: 87327-70-6(Hazardous Substances Data)

Usage

General Description

1-(2-chloro-6-fluorophenyl)ethan-1-ol, also known as 2-Chloro-6-fluorobenzyl alcohol, is a chemical compound with the molecular formula C8H8ClFO. It is a colorless liquid with a phenolic odor, commonly used as a chemical intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-(2-chloro-6-fluorophenyl)ethan-1-ol is often utilized in the production of antihistamines and muscle relaxants. It is also known for its antimicrobial properties and is used as an antiseptic and disinfectant. 1-(2-chloro-6-fluorophenyl)ethan-1-ol is considered to be a versatile chemical with various industrial applications. However, as with any chemical, proper handling and safety precautions should be observed when using this compound.

Upstream product

• 87327-69-3 1-(2-chloro-6-fluorophenyl)ethan-1-one 

Downstream Products

• 1000922-53-1 1-(2-chloro-6-fluorophenyl)ethan-1-amine 

Relevant articles and documents

ATF6 MODULATORS AND USES THEREOF

Compounds (I) as modulators of Activating Transcription Factor 6 (ATF6) are provided. The compounds may find use as therapeutic agents for the treatment of diseases or disorders mediated by ATF6 and may find particular use in the treatment of viral infections, neurodegenerative diseases, vascular diseases, or cancer.

Transaminases applied to the synthesis of high added-value enantiopure amines

Critical parameters affecting the stereoselective amination of (hetero)aromatic ketones using transaminases have been studied, such as temperature, pH, substrate concentration, cosolvent, and source and percentage of amino donor, to further optimize the production of enantiopure amines using both (S)- and (R)-selective biocatalysts from commercial suppliers. Interesting enantiopure amino building blocks have been obtained, overcoming some limitations of traditional chemical synthetic methods. Representative processes were scaled up, affording halogenated and heteroaromatic amines in enantiomerically pure form and good isolated yields.

2-(SUBSTITUTED PHENYL)-6-AMINO-5-ALKOXY, THIOALKOXY AND AMINOALKYL-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES

2-(Substituted phenyl)-6-amino-5-alkoxy, thioalkoxy and aminoalkyl-4-pyrimidinecarboxylic acid and its derivatives are potent herbicides demonstrating broad spectrum of weed control.