110065-18-4Relevant articles and documents
NUCLEOPHILIC CATALYSIS OF THE AMINOLYSIS OF ACTIVATED VINYL HALIDES BY ORGANIC BASES
Kravchenko, V. V.,Popov, A. F.,Kotenko, A. A.
, p. 1601 - 1605 (2007/10/02)
The existence of nucleophilic catalysis in the aminolysis of activated vinyl halides has been revealed.The limits and conditions of catalysis have been established from the results of a stepwise investigation of the kinetics of the processes occurring (the rate is limited by the formation or consumption of the intermediate vinylammonium salt).The nucleophilic catalysts studied form the following series in the efficiency of their action in SNVin-substitution involving amines in acetonitrile: 4-isopropylpyridine > pyridine > trimethylamine > 4-N,N-dimethylaminopyridine N-oxide > N-methylimidazole > N-methylpiperidine.
