110104-60-4

Usage

Chemical Properties

CLEAR YELLOW LIQUID AFTER MELTING

InChI:InChI=1/C6H9ClO3/c1-9-5(4-7)3-6(8)10-2/h3H,4H2,1-2H3/b5-3+

Upstream product

• 67-56-1 methanol 
• 32807-28-6 Methyl 4-chloroacetoacetate 
• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 149-73-5 trimethyl orthoformate 
• 41295-64-1 4-chloroacetoacetyl chloride 

Downstream Products

• 678149-15-0 1-((R)-2-Hydroxy-1-phenyl-ethyl)-4-methoxy-1,5-dihydro-pyrrol-2-one 
• 1268344-86-0 1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-5-D-1H-pyrrol-2(5H)-one 
• 1268344-87-1 1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-5-methyl-1H-pyrrol-2(5H)-one 
• 1268344-88-2 1-[(S)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-5-methyl-1H-pyrrol-2(5H)-one 
• 1268344-89-3 5-ethyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-90-6 5-ethyl-1-[(S)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-91-7 (R)-5-ethyl-1-[(R)-1-(3-ethyl-4-methoxyphenyl)-2-hydroxyethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-92-8 5-butyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-93-9 5-butyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-94-0 (R)-5-butyl-1-[(R)-1-(3-butyl-4-methoxyphenyl)-2-hydroxyethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-95-1 5-hexyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1Hpyrrol-2(5H)-one 
• 1268344-96-2 5-hexyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1Hpyrrol-2(5H)-one 
• 1268344-97-3 (R)-5-hexyl-1-[(R)-1-(3-hexyl-4-methoxyphenyl)-2-hydroxyethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-98-4 5-allyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1Hpyrrol-2(5H)-one 

Relevant academic research and scientific papers

Synthesis of new 3,3-dimethoxyazetidine-2-carboxylic acid derivatives

Cyclization of γ-amino-α-bromocarboxylic esters resulted in an efficient synthesis of new 3,3-dimethoxyazetidine-2-carboxylates, that is, methyl N-t-butyl-3,3-dimethoxyazetidine-2-carboxylic ester and 3,3-dimethoxyazetidine-2-carboxylic acid, or 3-bromo-4

Synthesis of 4-alkyl-1-benzhydryl-2-(methoxymethyl)azetidin-3-ols by regio- and stereoselective alkylation of 1-benzhydryl-3-(N-alkyl)imino-2-(methoxymethyl)azetidine

The regio- and stereoselective alkylation at the position C-4 of 1-alkyl-2-substituted azetidin-3-ones was investigated. Imination of 1-benzhydryl-2-methoxymethylazetidin-3-one, followed by alkylation under kinetic conditions and final hydrolysis of the imino group, gave 4-alkyl-1-benzhydryl-2-methoxymethylazetidin-3-ones in which the susbstituents at C-2 and C-4 had the cis stereochemistry. The reduction of the carbonyl group afforded the corresponding 4-alkyl-1-benzhydryl-2-methoxymethylazetidin-3-ols. The structure and the stereochemistry of the azetidinols were confirmed by single crystal X-ray diffraction analysis.

Methyl (E)-4-chloro-3-methoxy-2-butenoate: An extremely versatile four carbon building block

Methyl (E)-4-chloro-3-methoxy-2-butenoate (3a) is inexpensively prepared from methyl 4-chloroacetoacetate using thionyl chloride and methanol on an industrial scale. Many nucleophilic substitution reactions of chloride, which are impossible with the unpro

Process for the production of 4-chloro-3-alkoxy-but-2E-enoic acid alkyl esters

A process for the production of 4-chloro-3-alkoxy-but-2E-enoic acid alkyl esters starting from 4-chloroacetoacetic acid chloride by reaction with a dialkyl sulfite. The produced intermediate products are used as structural elements for, i.a., pharmaceutical agents.

Process for the production of 4-alkoxy-2(5H) thiophenones

Process for the production of 4-alkoxy-2(5H) thiophenones, which are suitable as intermediate products, i.e., for the production of highly pure thiotetronic acid.