110104-60-4

Basic information

• Product Name: METHYL (E)-4-CHLORO-3-METHOXY-2-BUTENOATE
• Synonyms: METHYL (E)-4-CHLORO-3-METHOXY-2-BUTENOATE;METHYL 4-CHLORO-3-METHOXY-(E)-2-BUTENOATE;(E)-4-CHLORO-3-METHOXY-2-BUTENOIC ACID METHYL ESTER;4-CHLORO-3-METHOXY-2(E)-BUTENOIC ACID METHYL ESTER;Methyl(E)-4-Chloro-3-Methoxy-2-butanoate;(E)-4-Methyl-3-methoxy-2-butenic acid;Methyl 4-chloro-3-methoxy-2-(E)-butenoate, GC 98%;(E)-METHYL 4-CHLORO-3-METHOXYBUT-2-ENOATE
• CAS NO: 110104-60-4
• Molecular Formula: C₆H₉ClO₃
• Molecular Weight: 164.59
• EINECS: 1312995-182-4
• Product Categories: API intermediates
• Mol File: 110104-60-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 25 °C
• Boiling Point: 95-97 °C (15.002 mmHg)
• Flash Point: 104 °C
• Appearance: clear yellow liquid after melting
• Density: 1.21 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0643mmHg at 25°C
• Refractive Index: 1.483-1.485
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Water Solubility: Insoluble
• CAS DataBase Reference: METHYL (E)-4-CHLORO-3-METHOXY-2-BUTENOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL (E)-4-CHLORO-3-METHOXY-2-BUTENOATE(110104-60-4)
• EPA Substance Registry System: METHYL (E)-4-CHLORO-3-METHOXY-2-BUTENOATE(110104-60-4)

Safety Data

• Hazard Codes: C
• Statements: 34-22
• Safety Statements: 45-36/37/39-26
• RIDADR: 3261
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 110104-60-4(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR YELLOW LIQUID AFTER MELTING

InChI:InChI=1/C6H9ClO3/c1-9-5(4-7)3-6(8)10-2/h3H,4H2,1-2H3/b5-3+

Upstream product

• 41295-64-1 4-chloroacetoacetyl chloride 
• 67-56-1 methanol 
• 32807-28-6 Methyl 4-chloroacetoacetate 
• 6192-52-5 p-toluenesulfonic acid monohydrate 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 79208-35-8 (Z)-5-benzylidene-1,5-dihydro-4-methoxypyrrol-2-one 
• 1268344-86-0 1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-5-D-1H-pyrrol-2(5H)-one 
• 1268344-87-1 1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-5-methyl-1H-pyrrol-2(5H)-one 
• 1268344-88-2 1-[(S)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-5-methyl-1H-pyrrol-2(5H)-one 
• 1268344-89-3 5-ethyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-90-6 5-ethyl-1-[(S)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-91-7 (R)-5-ethyl-1-[(R)-1-(3-ethyl-4-methoxyphenyl)-2-hydroxyethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-92-8 5-butyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-93-9 5-butyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-94-0 (R)-5-butyl-1-[(R)-1-(3-butyl-4-methoxyphenyl)-2-hydroxyethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-95-1 5-hexyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1Hpyrrol-2(5H)-one 
• 1268344-96-2 5-hexyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1Hpyrrol-2(5H)-one 
• 1268344-97-3 (R)-5-hexyl-1-[(R)-1-(3-hexyl-4-methoxyphenyl)-2-hydroxyethyl]-4-methoxy-1H-pyrrol-2(5H)-one 
• 1268344-98-4 5-allyl-1-[(R)-2-hydroxy-1-(4-methoxyphenyl)ethyl]-4-methoxy-1Hpyrrol-2(5H)-one 

Relevant articles and documents

Synthesis of new 3,3-dimethoxyazetidine-2-carboxylic acid derivatives

Cyclization of γ-amino-α-bromocarboxylic esters resulted in an efficient synthesis of new 3,3-dimethoxyazetidine-2-carboxylates, that is, methyl N-t-butyl-3,3-dimethoxyazetidine-2-carboxylic ester and 3,3-dimethoxyazetidine-2-carboxylic acid, or 3-bromo-4

Methyl (E)-4-chloro-3-methoxy-2-butenoate: An extremely versatile four carbon building block

Methyl (E)-4-chloro-3-methoxy-2-butenoate (3a) is inexpensively prepared from methyl 4-chloroacetoacetate using thionyl chloride and methanol on an industrial scale. Many nucleophilic substitution reactions of chloride, which are impossible with the unpro

Process for the production of 4-chloro-3-alkoxy-but-2E-enoic acid alkyl esters

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