110109-85-8Relevant academic research and scientific papers
Synthesis of (2R,8′S,3′E)-δ-tocodienol, a tocoflexol family member designed to have a superior pharmacokinetic profile compared to δ-tocotrienol
Liu, Xingui,Gujarathi, Satheesh,Zhang, Xuan,Shao, Lijian,Boerma, Marjan,Compadre, Cesar M.,Crooks, Peter A.,Hauer-Jensen, Martin,Zhou, Daohong,Zheng, Guangrong
, p. 4001 - 4006 (2016)
A group of side chain partially saturated tocotrienol analogues, namely tocoflexols, have been previously designed in an effort to improve the pharmacokinetic properties of tocotrienols. (2R,8′S,3′E)-δ-Tocodienol (1) was predicted to be a high value tocof
ASYMMETRIC REDUCTION OF FARNESOL
Julia, Marc,Roy, Pierre
, p. 5003 - 5010 (2007/10/02)
Asymmetric hydroboration-oxidation followed by reductive deoxygenation has been used to bring about the asymmetric hydrogenation of simple trisubstituted olefins.This technique has been illustrated by the preparation of (R)-(-)-6,7,10,11-tetrahydrofarnesol.
