110109-87-0

Upstream product

• 110109-85-8 (R)-[(3,7-dimethyloct-6-en-1-yl)sulfonyl]benzene 
• 873-55-2 sodium benzenesulfonate 
• 67214-54-4 (R)-citronellyl tosylate 
• 1117-60-8 (R)-3,7-dimethyloctan-1-ol 
• 1117-61-9 (3R)-citronellol 

Downstream Products

• 201154-01-0 (2R,6R)-1-Methoxymethoxy-2,6,10-trimethyl-undecane 
• 131636-78-7 (2R,6R)-2,6,10-trimethylundecyl tosylate 
• 110109-98-3 3,7,11-trimethyl-5-benzenesulfonyl-2E-dodecen-1-yl acetate 

Relevant academic research and scientific papers

Enzymatic Preparation of Enantiomerically Pure Alkan-2- and -3-ols by Lipase Catalysed Hydrolysis with Pseudomonas cepacia in the Presence of Organic Media

Pseudomonas cepacia lipase-catalysed hydrolysis of the acetates of racemic alkan-2- and -3-ols was carried out in the presence of organic media.Good to high enantioselectivity was observed in an acetone-water solvent system, the system leading to (R)-alcohols of 80-96percent ee.Enantioselectivity can be affected by the presence of the double bond in the unsaturated acetate prepared from an alkenol.The increased enantioselectivity observed for an acetone-water reaction system was utilized in the synthesis of optically active natural products possessing alkan-2-ol skeletons, such as (2R,6R,10R)-6,10,14-trimethyl pentadecan-2-ol, the natural form of the sex pheromone of Corcyra cephalonica, and (R)-sulcatol, an aggregation pheromone of ambrosia beetles.

ASYMMETRIC REDUCTION OF FARNESOL

Asymmetric hydroboration-oxidation followed by reductive deoxygenation has been used to bring about the asymmetric hydrogenation of simple trisubstituted olefins.This technique has been illustrated by the preparation of (R)-(-)-6,7,10,11-tetrahydrofarnesol.