1101119-08-7

Basic information

• Product Name: N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-N-methyl-2-(methyl(2-morpholinoethyl)amino)-5-nitrobenzenesulfonohydrazide hydrochloride
• Synonyms: N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-N-methyl-2-(methyl(2-morpholinoethyl)amino)-5-nitrobenzenesulfonohydrazide hydrochloride
• CAS NO: 1101119-08-7
• Molecular Weight: 563.037
• Mol File: 1101119-08-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-N-methyl-2-(methyl(2-morpholinoethyl)amino)-5-nitrobenzenesulfonohydrazide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-N-methyl-2-(methyl(2-morpholinoethyl)amino)-5-nitrobenzenesulfonohydrazide hydrochloride(1101119-08-7)
• EPA Substance Registry System: N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-N-methyl-2-(methyl(2-morpholinoethyl)amino)-5-nitrobenzenesulfonohydrazide hydrochloride(1101119-08-7)

Safety Data

• Hazardous Substances Data: 1101119-08-7(Hazardous Substances Data)

Upstream product

• 41239-40-1 methyl-(2-morpholin-4-yl-ethyl)-amine 
• 1101118-97-1 N'-((5-cyanopyrazolo[1,5-a]pyridin-3-yl)methylene)-2-fluoro-N-methyl-5-nitrobenzenesulfonohydrazide 

Relevant articles and documents

Novel pyrazolo[1,5-a]pyridines with improved aqueous solubility as p110α-selective PI3 kinase inhibitors

As part of our investigation into pyrazolo[1,5-a]pyridines as novel p110α selective PI3 kinase inhibitors, we report a range of analogues with improved aqueous solubility by the addition of a basic amine. The compounds demonstrated comparable p110α potency and selectivity to earlier compounds but with up to 1000× greater aqueous solubility, as the hydrochloride salts. The compounds also displayed good activity in a cellular assay of PI3 kinase activity.