41239-40-1Relevant academic research and scientific papers
COMPOUNDS THAT INHIBIT MCL-1 PROTEIN
-
Page/Page column 743, (2018/10/25)
Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (I), or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.
Compounds and methods for inhibiting phosphate transport
-
Page/Page column 234, (2016/05/02)
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, A, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1
-
Paragraph 00608, (2016/04/26)
Provided herein are small molecule neurotensin receptor agonists, compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.
KINASE INHIBITORS
-
Page/Page column 209; 210, (2013/06/27)
Compounds of formula (I) or a pharmaceutically acceptable salt thereof: formula (I) wherein R2, W, A, Y and R1 are as defined in the specification, are p38 MAPK inhibitors, useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
KINASE INHIBITORS
-
Paragraph 0830; 0831, (2013/06/27)
Compounds of formula (I) and pharmaceutically acceptable salts thereof: wherein R2, W, A, Y and R1 are as defined in the specification, are p38 MAPK inhibitors, and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.
C-4" POSITION SUBSTITUTED MACROLIDE DERIVATIVE
-
Page/Page column 64, (2012/09/11)
A macrolide compound represented by the formula (I) effective against erythromycin resistant bacteria (for example, resistant pneumococci, streptococci and mycoplasmas).
COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
-
Page/Page column 72, (2012/02/01)
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically ac
COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
-
Page/Page column 45-46, (2012/02/01)
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically ac
COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
-
Page/Page column 52, (2012/02/01)
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically ac
INHIBITORS OF ANTHRAX LETHAL FACTOR
-
Page/Page column 66, (2008/06/13)
Methods, compounds and compositions for preventing and treating anthrax infections by inhibiting Anthrax Lethal Factor (LF) activity.
