11013-55-1Relevant academic research and scientific papers
Construction of "normal"- and "iso-type" oxazolidine rings in C20-diterpenoid alkaloids: Oxidative cyclization with potassium ferricyanide
Pelletier, S.William,Ateya, Abdel-Monem M.,Mody, Naresh V.,Desai, Haridutt K.,Schramm, Lee C.
, p. 3647 - 3650 (2007/10/02)
An efficient and simple method using alkaline ferricyanide for converting the NCH2CH2OH group-containing alkaloid derivatives into their "normal"- and "iso-type"-oxazolidine ring-containing alkaloids has been developed. This is the first one-step oxidation method which affords both types of oxazolidine rings simultaneously.
FORMATION OF THE OXAZOLIDINE RING IN C20-DITERPENOID ALKALOIDS BY OXIDATIVE CYCLIZATION WITH SILVER OXIDE
Pelletier, S. William,Ateya, Abdel-Monem M.,Mody, Naresh V.,Schramm, Lee C.
, p. 1155 - 1157 (2007/10/02)
Treatment of the N-CH2-CH2OH group containing alkaloids with silver oxide in alcohol affords the "iso-type" oxazolidine ring-containing alkaloids in yield 72 to 90percent via oxidative cyclization.This method affords higher yields than earlier reported methods for this type transformation.
