11014-01-0

Basic information

• Product Name: (+/-)-dihydrohippeastrine
• CAS NO: 11014-01-0
• Molecular Weight: 317.342
• Mol File: 11014-01-0.mol

Chemical Properties

• CAS DataBase Reference: (+/-)-dihydrohippeastrine(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-dihydrohippeastrine(11014-01-0)
• EPA Substance Registry System: (+/-)-dihydrohippeastrine(11014-01-0)

Safety Data

• Hazardous Substances Data: 11014-01-0(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 67-56-1 methanol 
• 94023-80-0 Acetic acid (3aR,5R,6R,7R,7aS)-5-acetoxy-7-(6-acetoxymethyl-benzo[1,3]dioxol-5-yl)-1-methyl-2-oxo-octahydro-indol-6-yl ester 
• 94013-29-3 Acetic acid 6-((1aR,2aS,5aR,6S,6aS)-5-methyl-4-oxo-octahydro-1-oxa-5-aza-cyclopropa[f]inden-6-yl)-benzo[1,3]dioxol-5-ylmethyl ester 
• 94013-31-7 Acetic acid 6-((3aR,7R,7aS)-1-methyl-2-oxo-2,3,3a,4,7,7a-hexahydro-1H-indol-7-yl)-benzo[1,3]dioxol-5-ylmethyl ester 
• 94013-30-6 (3aS,7S,7aR)-7-Benzo[1,3]dioxol-5-yl-1-methyl-1,3,3a,4,7,7a-hexahydro-indol-2-one 
• 94013-32-8 (3aR,7R,7aS)-7-Benzo[1,3]dioxol-5-yl-1,3,3a,4,7,7a-hexahydro-indol-2-one 
• 42390-68-1 methyl 2c-(N-methoxycarbonylamino)-3t-(3,4-methylenedioxyphenyl)cyclohex-4-enyl-r-acetate 
• 94013-22-6 C₁₇H₁₇NO₆ 

Relevant articles and documents

Total synthesis of (±)-8-Oxo-erythrinine, (±)-8-oxo-erythraline, and (±)-clivonine

Total syntheses of the erythrina alkaloids (±)-8-oxo-erythrinine and (±)-8-oxo-erythraline have been developed, based on a substrate-controlled intramolecular 6-exo-trig selective radical spirocyclization that establishes the quaternary center of the B-ri

Total synthesis of the lycorenine-type amaryllidaceae alkaloid (±)-Clivonine via a biomimetic ring-switch from a lycorine-type progenitor

A fully diastereoselective total synthesis of the lycorenine-type Amaryllidaceae alkaloid (±)-clivonine (19) is reported via a route that employs for the first time a biomimetic ring-switch from a lycorine-type progenitor, thereby corroborating experimentally the biogenetic hypothesis first expounded for these compounds by Barton in 1960.

Total synthesis of the Amaryllidaceae alkaloid clivonine

Two syntheses of the Amaryllidaceae alkaloid clivonine (1) are described. Both employ previously reported 7-arylhydrindane 6 as an intermediate but differ in the method employed for subsequent introduction of what becomes the ring-B lactone carbonyl carbon (C7). The synthesis featuring a Bischler-Napieralski reaction for this transformation constitutes the first asymmetric synthesis of natural (+)-clivonine. Crystal structures for compounds (±)-13, (±)-16, (-)-20 and (±)-28 are also reported.

SYNTHESIS OF AN AMARYLLIDACEAE ALKALOID, (+/-)-HIPPEASTRINE

Total synthesis of one of Amaryllidaceae alkaloids, hippeastrine, was accomplished starting from methyl 2c-(N-methoxycarbonylamino)-3t-(3,4-methylenedioxyphenyl)cyclohex-4-enyl-r-acetate in stereoselective manner.