110164-66-4Relevant academic research and scientific papers
Two novel and potent 3-[(o-Methoxyphenyl)piperazinylethyl]-5-phenylthieno[2,3-d]pyrimidine-2, 4-diones selective for the α1D receptor
Carroll, William A.,Sippy, Kevin B.,Esbenshade, Timothy A.,Buckner, Steven A.,Hancock, Arthur A.,Meyer, Michael D.
, p. 1119 - 1121 (2007/10/03)
The synthesis and in vitro characterization of A-119637 and A-123189, two novel, selective and potent α1D antagonists, are described.
Thiophene Systems. 9. Thienopyrimidinedione Derivatives as Potential Antihypertensive Agents
Russell, Ronald K.,Press, Jeffrey B.,Rampulla, Richard A.,McNally, James J.,Falotico, Robert,et al.
, p. 1786 - 1793 (2007/10/02)
A series of thieno-, thieno-, and thienopyrimidine-2,4-diones with (phenylpiperazinyl)alkyl substitution at N-3 have been synthesized and evaluated for antihypertensive effects in spontaneously hypertensive rats (SHR).These 49 compoun
Thienopyrimidine-2,4-dione derivatives and intermediates thereof
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, (2008/06/13)
The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are generally vasodilating agents and anti-hypertensive agents. The compounds are us
