1101869-64-0

Basic information

• Product Name: C₃₄H₃₇NO₆
• Synonyms: C₃₄H₃₇NO₆
• CAS NO: 1101869-64-0
• Molecular Weight: 555.671
• Mol File: 1101869-64-0.mol

Chemical Properties

• CAS DataBase Reference: C₃₄H₃₇NO₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₃₇NO₆(1101869-64-0)
• EPA Substance Registry System: C₃₄H₃₇NO₆(1101869-64-0)

Safety Data

• Hazardous Substances Data: 1101869-64-0(Hazardous Substances Data)

Upstream product

• 2859-78-1 4-Bromoveratrole 
• 537030-19-6 (2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-3,4-dihydro-2H-pyrrole 1-oxide 

Downstream Products

• 1101869-65-1 (2R,3R,4R,5R)-2-(3,4-dimethoxyphenyl)-5-(hydroxymethyl)pyrrolidine-3,4-diol 

Relevant articles and documents

Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library

Inspired by polyhydroxylated pyrrolidine alkaloid natural products, a 18-membered library of 2-aryl polyhydroxylated pyrrolidines has been efficiently prepared in two or three synthetic steps from the known chiral cyclic nitrones with high yield and purity and excellent stereoselectivity. The inhibitory activity of all these compounds against various glycosidase enzymes was evaluated. Interestingly, 15 and 19 show better inhibitory activities than radicamine A (20) and B (18) against α-glucosidases. The IC50 values of 15 and 19 are 1.1 and 0.5 μM, respectively. In this study, we also discovered the substituent(s) on the aryl ring could affect the inhibition potency and selectivity against glycosidases.