537030-19-6Relevant articles and documents
Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars
Bojarová, Pavla,Carmona, Ana T.,K?en, Vladimír,Kulik, Natalia,Mészáros, Zuzana,Martínez-Bailén, Macarena,Moreno-Vargas, Antonio J.,Pingitore, Valeria,Robina, Inmaculada,Slámová, Kristyna
, (2022/02/14)
Two libraries of mono- and dimeric pyrrolidine iminosugars were synthesized by CuAAC and (thio)urea-bond-forming reactions from the respective azido/aminohexylpyrrolidine iminosugar precursors. The resulting monomeric and dimeric compounds were screened f
Small structure tree alkali compound and its preparation method and application
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Paragraph 0099; 0100; 0106; 0107, (2018/09/26)
The invention relates to a Broussonetia kazinoki alkaline compound. Structure of the compound is shown as a formula (1). The invention further provides a preparation method of the compound, a glycosidase inhibitor by using the compound or the compound prepared by the method as an active ingredient and application of the compound or the compound, prepared by the method, serving as an active ingredient in preparing drug. The Broussonetia kazinoki alkaline compound has high glycosidase inhibiting activity and potential medicinal value.
Synthesis and glycosidase inhibition potency of all-trans substituted 1-C-perfluoroalkyl iminosugars
Massicot, Fabien,Plantier-Royon, Richard,Vasse, Jean-Luc,Behr, Jean-Bernard
, p. 2 - 7 (2018/05/24)
Synthetic analogues of the naturally occurring iminosugar homoDMDP, which feature a perfluoroalkyl group at the pseudo-anomeric position, have been synthesized from the corresponding sugar-derived cyclic aldonitrone. The new fluorinated iminosugars as wel