110237-87-1Relevant academic research and scientific papers
Synthesis of furanose glycals from furanose 1,2-diols and their cyclic thiocarbonate esters
Robles Diaz, Rafael,Rodriguez Melgarejo, Conception,Izquierdo Cubero, Isidoro,Plaza Lopez-Espinosa, Maria T.
, p. 375 - 380 (2007/10/03)
Two new methods for the synthesis of furanoid glycals are described. Both procedures were shown to be faster and cheaper that those previously reported. Protected 1,2-dihydroxypento- and hexo-furanose derivatives with the D-xylo, D-gluco and D-ribo, D-all
Synthesis and glycosidic reaction of 1,2-anhydromanno-, lyxo-, gluco-, and xylofuranose perbenzyl ethers
Du, Yuguo,Kong, Fanzuo
, p. 797 - 817 (2007/10/03)
Stereospecific synthesis of 1,2-anhydromanno-, lyxo-, gluco-, and xylofuranose perbenzyl ethers was successfully achieved via intramolecular SN2 reaction of the corresponding C-1 alkoxide with C-2 bearing tosyloxy group. The key intermediates, furanose 2-sulfonates, were prepared from the corresponding 1,2-diols and tosyl chloride under phase transfer conditions in good yields. Condensation of the anhydro sugars with 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose or N-benzyloxycarbonyl L-serine methyl ester in the absence of catalyst gave 1,2-trans-linked glycofuranosides in high yield.
