110237-99-5

Basic information

• Product Name: ibu-dmt-deoxyguanosine H-phosphonate*triethylammo
• CAS NO: 110237-99-5
• Molecular Formula: C₃₅H₃₈N₅O₉P
• Molecular Weight: 804.88
• Mol File: 110237-99-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ibu-dmt-deoxyguanosine H-phosphonate*triethylammo(CAS DataBase Reference)
• NIST Chemistry Reference: ibu-dmt-deoxyguanosine H-phosphonate*triethylammo(110237-99-5)
• EPA Substance Registry System: ibu-dmt-deoxyguanosine H-phosphonate*triethylammo(110237-99-5)

Safety Data

• Hazardous Substances Data: 110237-99-5(Hazardous Substances Data)

Upstream product

• 160107-22-2 N₂-isobutyryl-3'-O-(2-cyanoethyl)-phosphonate-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 
• 68892-41-1 5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine 

Downstream Products

• 71065-98-0 4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)-N²-isobutyryl-2'-deoxyguanosin-3'-yl phosphate 

Relevant articles and documents

Solution-phase synthesis of branched DNA hybrids via H -phosphonate dimers

A method for the solution-phase synthesis of branched oligonucleotides with tetrahedral or pseudo-octahedral geometry is described that involves the coupling of 3′-H-phosphonates of protected dinucleoside phosphates and organic core molecules. The dimer building blocks are produced by a synthesis that requires no chromatographic purification and that produces the dimer H-phosphonates in up to 44% yield in less than three days of laboratory work. A total of seven different branched hybrids were prepared, including a new hybrid of the sequence (CG)4TBA, where TBA stands for tetrakis(p- hydroxybiphenyl)adamantane that assembles into a material from micromolar aqueous solution upon addition of MgCl2.

NUCLEOSIDE H-PHOSPHONATES. III. CHEMICAL SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES BY THE HYDROGENPHOSPHONATE APPROACH

A rapid synthesis of oligodeoxyribonucleotides on solid support is described via coupling of the deoxyribonucleoside 3'-H-phosphonates in the presence of various condensing reagents.