160107-22-2

Basic information

• Product Name: N₂-isobutyryl-3'-O-(2-cyanoethyl)-phosphonate-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine
• Synonyms: N₂-isobutyryl-3'-O-(2-cyanoethyl)-phosphonate-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine
• CAS NO: 160107-22-2
• Molecular Weight: 756.752
• Mol File: 160107-22-2.mol

Chemical Properties

• CAS DataBase Reference: N₂-isobutyryl-3'-O-(2-cyanoethyl)-phosphonate-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine(CAS DataBase Reference)
• NIST Chemistry Reference: N₂-isobutyryl-3'-O-(2-cyanoethyl)-phosphonate-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine(160107-22-2)
• EPA Substance Registry System: N₂-isobutyryl-3'-O-(2-cyanoethyl)-phosphonate-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine(160107-22-2)

Safety Data

• Hazardous Substances Data: 160107-22-2(Hazardous Substances Data)

Upstream product

• 78635-98-0 3'-O-levulinoylthymidine 
• 141846-56-2 5'-O-dimethoxytrityl-N2-isobutyryl-2'-deoxyguanosine-3'-O-(2-cyanoethyl)-N,N-diisopropylphosphoramidite 
• 68892-42-2 N-isobutyryl-2'-deoxyguanosine 
• 68892-41-1 5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine 
• 109-78-4 3-Hydroxypropionitrile 
• 961-07-9 2'-Deoxyguanosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 93134-41-9 N²-isobutyryl-3'-O-levulinyl-2'-deoxyguanosine 
• 91592-66-4 N-benzoyl-3'-O-levulinoyl-2'-deoxy-β-D-cytidine 

Downstream Products

• 110237-99-5 C₃₅H₃₈N₅O₉P 
• 68892-41-1 5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine 

Relevant articles and documents

COMPOUNDS FOR TREATING BACTERIAL INFECTIONS

The present invention relates to a novel class of guanine nucleotide analogs which inhibit RelA and Relseq synthetic activity and which possess anti-bacterial activity. The present invention also relates to pharmaceutical compositions that include such compounds, and to methods of use of such compounds or compositions for combating bacteria and treating bacterial infections.

High-yield solution-phase synthesis of di- and trinucleotide blocks assisted by polymer-supported reagents

(Chemical Equation Presented) A new solution-phase phosphoramidite approach is reported for oligonucleotide synthesis employing recyclable solid-supported reagents. It uses polyvinyl pyridinium tosylate as the activator of a nucleoside-3′-O-phosphoramidit