110254-69-8

Basic information

• Product Name: 3-benzyl-4-chloro-1-methylquinolin-2(1H)-one
• CAS NO: 110254-69-8
• Molecular Formula: C₁₇H₁₄ClNO
• Molecular Weight: 283.7522
• Mol File: 110254-69-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 404.8°C at 760 mmHg
• Flash Point: 198.6°C
• Density: 1.28g/cm³
• Vapor Pressure: 9.19E-07mmHg at 25°C
• Refractive Index: 1.652
• CAS DataBase Reference: 3-benzyl-4-chloro-1-methylquinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-4-chloro-1-methylquinolin-2(1H)-one(110254-69-8)
• EPA Substance Registry System: 3-benzyl-4-chloro-1-methylquinolin-2(1H)-one(110254-69-8)

Safety Data

• Hazardous Substances Data: 110254-69-8(Hazardous Substances Data)

Upstream product

• 72587-96-3 3-benzyl-4-hydroxy-1-methylquinolin-2(1H)-one 

Downstream Products

• 110229-46-4 3-benzyl-1-methyl-1H-quinolin-2-one 
• 110216-83-6 4-amino-3-benzyl-1-methylquinolin-2(1H)-one 
• 110216-94-9 3-Benzyl-1-methyl-4-tosyloxy-2(1H)-chinolon 
• 72587-96-3 3-benzyl-4-hydroxy-1-methylquinolin-2(1H)-one 

Relevant articles and documents

Reaction of some 2-quinolone derivatives with phosphoryl chloride: Synthesis of novel phosphoric acid esters of 4-hydroxy-2-quinolone

3-Chloroquinoline-2,4-diones do not react with phosphoryl chloride, however, 2,4-dichloroquinolines and/or 4-chloroquinolin-2-ones are formed in the presence of N,N-dimethylaniline. Along with these compounds, small quantities of novel dihydrogen phosphates of 4-hydroxyquinolin-2-ones were isolated. We outline a simple procedure that allows for the preparation of these compounds in moderate to good yields. All compounds were characterized by 1H and 13C NMR, IR, EI-MS, and ESI-MS spectroscopy, and in select cases by 31P NMR spectroscopy.