110270-42-3 Usage
General Description
(R)-(+)-1-Fluoro-2-octanol is a chemical compound with the molecular formula C8H17FO. It is a colorless liquid with a faint, sweet odor, and it is soluble in organic solvents. (R)-(+)-1-FLUORO-2-OCTANOL is primarily used in organic synthesis as a building block for various pharmaceutical and agrochemical products. It is also used as a chiral auxiliary in asymmetric synthesis to control the stereochemistry of reactions. Additionally, (R)-(+)-1-fluoro-2-octanol has potential applications in the production of flavors and fragrances. Its ability to be used as a chiral building block makes it valuable in the development of new compounds with specific stereochemical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 110270-42-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,0,2,7 and 0 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 110270-42:
(8*1)+(7*1)+(6*0)+(5*2)+(4*7)+(3*0)+(2*4)+(1*2)=63
63 % 10 = 3
So 110270-42-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H17FO/c1-2-3-4-5-6-8(10)7-9/h8,10H,2-7H2,1H3/t8-/m1/s1
110270-42-3Relevant articles and documents
SYNTHESIS OF OPTICALLY ACTIVE FLUORINATED MATERIALS BY USE OF IMMOBILIZED ENZYMES FOR ASYMMETRIC HYDROLYSIS
Kitazume, Tomoya,Okamura, Naoko,Ikeya, Takanobu,Yamazaki, Takashi
, p. 107 - 116 (1988)
A synthetic approach to optically active fluorinated compounds was based on the enantiotopic specificity of asymmetric hydrolysis by an immobilized enzyme.
Stereo- and regiocontrolled synthesis of fluorohydrins from optically active epoxides
Umezawa,Takahashi,Furuhashi,Nohira
, p. 2053 - 2060 (2007/10/02)
The hydrofluorination of optically active terminal epoxides, which were produced by a microbial reaction, with HF-amine reagents weer studied. 1,2-Epoxyoctane and glycidyl hexyl ether gave the corresponding 2-fluoro-1-alkanol derivatives with inversion of the asymmetric center with high stereospecificity, while in the hydrofluorination of pentafluorostyrene oxide and 2-methyl-1,2-epoxyhexane, partial racemization occurred. The basicity of the amine used, the HF/amine ratio in the HF-amine reagent, and the substituent on the epoxide affected the stereospecificity and regioselectivity of the hydrofluorination of the epoxides.
