110307-01-2Relevant academic research and scientific papers
ORTHO-LITHIATION OF 2-(BENZOTHIAZOL-2-YLTHIO)PYRIDINE. PREPARATION OF 2,3-DISUBSTITUTED PYRIDINES
Katritzky, Alan R.,Aurrecoechea, Jose M.,Miguel, Luis M. Vazquez de
, p. 427 - 436 (2007/10/02)
2-(Benzothiazol-2-ylthio)pyridine undergoes lithiation exclusively at the 3-position.The products of reaction with electrophiles of the lithiated species undergo sulfide cleavage to give 3-substituted 2-alkylthiopyridines and/or 3-substituted pyridine-2-thiones.
