110317-47-0Relevant articles and documents
Synthesis and antimicrobial activities of monoindolyl- and bisindolyloximes
Prudhomme, Michelle,Sancelme, Martine,Bonnefoy, Alain,Fabbro, Doriano,Meyer, Thomas
, p. 161 - 165 (1999)
Six monoindolyl- and bisindolyloximes structurally related to protein kinase C inhibitors bisindolylmaleimides were synthezised. They did not have protein kinase C inhibitory properties but exhibited interesting antimicrobial activities. Their antibacterial activities against several strains of pathogenic and non-pathogenic Gram-positive and Gram-negative bacteria are described. The bisindolyl monooxime isomers exhibited a marked activity against the three strains of Staphylococcus aureus tested and against Escherichia coli 1507E.