110317-48-1

Usage

Uses

Used in Organic Synthesis:
D,L-3-INDOLYLGLYCINE METHYL ESTER is used as a synthetic intermediate for the production of various organic compounds. Its ability to be easily modified and incorporated into larger molecules makes it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, D,L-3-INDOLYLGLYCINE METHYL ESTER is used as a key building block for the development of new drugs. Its unique structure can be utilized to create novel drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
D,L-3-INDOLYLGLYCINE METHYL ESTER is also used in the agrochemical industry as a starting material for the synthesis of new pesticides and other crop protection agents. Its versatility allows for the development of innovative products to address various agricultural challenges.
Used in Specialty Chemicals:
In the specialty chemicals sector, D,L-3-INDOLYLGLYCINE METHYL ESTER is employed as a raw material for the production of various specialty chemicals, such as dyes, fragrances, and other fine chemicals. Its unique properties enable the creation of high-value products with specific applications.

InChI:InChI=1/C11H12N2O2/c1-15-11(14)10(12)8-6-13-9-5-3-2-4-7(8)9/h2-6,10,13H,12H2,1H3

Upstream product

• 110317-55-0 (E)-2-(3-Indolyl)-2-(hydroxyimino)essigsaeure-methylester 
• 1069135-02-9 methyl 2-(diallylamino)-2-(1H-indol-3-yl)acetate 
• 120-72-9 indole 
• 1069135-00-7 methyl 2-(1,1,1,3,3,3-hexamethyldisilazan-2-yl)-2-methoxyacetate 
• 113975-75-0 methyl indol-3-ylglyoxylate oxime 
• 110317-47-0 (Z)-2-(3-Indolyl)-2-(hydroxyimino)essigsaeure-methylester 
• 18372-22-0 2-(3-indolyl)oxoacetic acid methyl ester 

Downstream Products

• 6747-15-5 α-amino-(+/)-3-indoleacetic acid 
• 294888-39-4 (+/-)-methyl-N-benzyloxycarbonyl-3-indoleglycinate 
• 294888-42-9 N-Cbz-indol-3-yl-N-methyl-O-methoxyglycinamide 
• 294888-41-8 (+/-)-N-benzyloxycarbonyl-3-indoleglycinate 
• 58237-94-8 N-Boc-indol-3-ylglycine 

Relevant academic research and scientific papers

A practical approach to non-natural or N-unsubstituted α-arylglycine derivatives: Hf(OTf)4-doped Me3SiCl system-catalyzed aminomethylation of electron-rich arenes with a new type of N,O-acetal

The authors have demonstrated the Hf(OTf)4-doped Me3SiCl system-catalyzed aminomethylation of electron-rich aromatic compounds, such as indoles and anilines, with new types of N,O-acetals having a variety of functional groups, such a

Syntheses of bis(3'-indolyl)-2(1H)-pyrazinones

The syntheses of 3,6-bis(3'-indolyl)-2(1H)-pyrazinone and 3,5- bis(3'indolyl)-2(1H)-pyrazinone were described. Syntheses of 3,6-bis(3'- indolyl)-2(1H)-pyrazinone proceeded through the condensation of N-Boc- indolylglycine with indol-3-yl-N-methyl-O-methox

Hexahydropyrroloindoles - Attempts to Synthesize 2-Indolyl Thioethers

The N-tryptamine derivatives 9, 11, 12, and 19 with the functional groups CN, CONH2, CO2H, and CO2Me, respectively, in the α position to the indole ring have been synthesized.Sensitized photooxiation of 9, 12, 19, N-Boc--tryptophan (21), and N-Boc-tryptamine (22) affords the hexahydropyrroloindoles 23-27, in the case of 11 the ring closure occurs at the amine nitrogen to give the ketone 28, N-Boc-homotryptamine (31) yields the hexahydropyridoindole 32, whereas no azetidine formation from 2-(3-indolyl)glycine (36) is observed.The oxi mes 34a and 34 b, intermediates in the synthesis of 36, have been separated chromatographically and characterized NMR spectroscopically as E and Z-isomers, respectively.- Attempts to introduce with cysteine derivatives a thioether group in position 2 of the compounds described above, failed. 21, 22, 26, 27, and N-Boc-2-(3-indolyl)propylamine (43), bearing a methyl group in the α position to the indole ring, and its photooxidation product 44 show only thin-layer chromatographically detectable thioether formation.