110330-98-8

Basic information

• Product Name: N,N′-(ethane-1,2-diyl)bis(N-benzyl-2-chloroacetamide)
• Synonyms: N,N′-(ethane-1,2-diyl)bis(N-benzyl-2-chloroacetamide)
• CAS NO: 110330-98-8
• Molecular Weight: 393.313
• Mol File: 110330-98-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N′-(ethane-1,2-diyl)bis(N-benzyl-2-chloroacetamide)(CAS DataBase Reference)
• NIST Chemistry Reference: N,N′-(ethane-1,2-diyl)bis(N-benzyl-2-chloroacetamide)(110330-98-8)
• EPA Substance Registry System: N,N′-(ethane-1,2-diyl)bis(N-benzyl-2-chloroacetamide)(110330-98-8)

Safety Data

• Hazardous Substances Data: 110330-98-8(Hazardous Substances Data)

Upstream product

• 79-04-9 chloroacetyl chloride 
• 140-28-3 N,N'-Dibenzylethylenediamine 

Downstream Products

• 103169-97-7 N,N'-dibenzyl-N,N'-bis-piperidinoacetyl-ethylenediamine 
• 102812-66-8 1,2-bis-[benzyl-(N,N-dimethyl-glycyl)-amino]-ethane 
• 125262-43-3 N,N',N''-tribenzyl-1,4,7-triazacyclononane 
• 4730-54-5 1,4,7-triazacyclononane 

Relevant articles and documents

Synthesis of Previously Inaccessible Derivatives of 1,4,7-Tri-R-1,4,7-Triazacyclononane, Including Chiral Examples, and a Rapid Synthesis of the HCl Salts of H3tacn and H4dtne

The synthesis of 1,4-di-tert-butyl-7-R-1,4,7-triazacyclononane (tBu2Rtacn) derivatives through a “crab-like” cyclization is reported. The tert-butyl groups were cleavable with concentrated hydrochloric acid, allowing for a facile and convenient synthesis of the HCl salt of H3tacn and the most direct route to its industrially relevant binucleating N-ethylene bridged derivative, H4dtne. In addition, the synthesis of chiral tacn derivatives with both one and two stereocenters in non-annulet, alpha-N positions is reported.