1103458-56-5Relevant articles and documents
The discovery of a selective, small molecule agonist for the mas-related gene X1 receptor
Wroblowski, Berthold,Wigglesworth, Mark J.,Szekeres, Philip G.,Smith, Graham D.,Rahman, Shahzad S.,Nicholson, Neville H.,Muir, Alison I.,Hall, Adrian,Heer, Jag P.,Garland, Stephen L.,Coates, William J.
experimental part, p. 818 - 825 (2009/12/03)
The novel 7-transmembrane receptor MrgX1 is located predominantly in the dorsal root ganglion and has consequently been implicated in the perception of pain. Here we describe the discovery and optimization of a small molecule agonist and initial docking s
